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E-book

Title Early life origins of human health and disease / editors, John P. Newnham, Michael G. Ross
Published Basel ; New York : Karger, ©2009

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Description 1 online resource (ix, 224 pages) : illustrations
Contents Developmental plasticity and the developmental origins of health and disease / P.D. Gluckman, M.A. Hanson -- Epigenetics and the influence of maternal diet / K.A Lillycrop, M.A. Hanson, G.C. Burdge -- The economics of developmental origins of health and disease : modelling the benefit of a healthy start to life / K.L. Franko, K.C. O'Connor, S.M.B. Morton -- Nutritional interventions in mothers to improve the health of the offspring : are we ready? / C.H.D. Fall, J.E. Harding, C.S. Yajnik -- Developmental origins of health and disease : the importance of environmental exposures / R. Newbold, J.J. Heindel -- Developmental origins of health and disease across generations : theory, observation, experiment / M.W. Gillman [and others] -- Early embryo environment and developmental potential / T.P. Fleming, K.D. Sinclair, K.L. Kind -- Early environmental influences on lung development : implications for lung function and respiratory health throughout life / R. Harding [and others] -- Development of the fetal hypothalamic-pituitary-adrenal-placental axis : implications for postnatal health / J. Challis [and others] -- Developmental origins of musculoskeletal disease / C. Cooper [and others]
Developmental origins of reproductive health / D.M. Sloboda, R. Hart, M. Hickey -- Developmental origins of immune tolerance : pathways and influences / S.L. Prescott -- Developmental programming of the kidney / M.J. Nijland, P.W. Nathanielsz -- Perinatal appetite programming / M. Desai, E. Keen-Rhinehart, M.G. Ross -- Fetal programming of type 2 diabetes / A. Piekarz, S.E. Ozanne -- Developmental origins of diabetes : interventional strategies / R.A. Simmons -- Prenatal risk factors for breast cancer and clues to the underlying biological mechanisms from animal and human studies / R. Troisi, I. dos Santos Silva, R. Newbold -- The offspring of women with severe mental disorder / V.A. Morgan [and others] -- Approaches to evaluate gene-environment interactions underlying the developmental origins of health and disease / C.E. Pennell [and others]
Developmental plasticity and the developmental origins of health and disease / P.D. Gluckman, M.A. Hanson -- Epigenetics and the influence of maternal diet / K.A Lillycrop, M.A. Hanson, G.C. Burdge -- The economics of developmental origins of health and disease : modelling the benefit of a healthy start to life / K.C. O'Connor, K.L. Franko, S.M.B. Morton -- Nutritional interventions in mothers to improve the health of the offspring : are we ready? / C.H.D. Fall, J.E. Harding, C.S. Yajnik -- Developmental origins of health and disease : the importance of environmental exposures / R.R. Newbold, J.J. Heindel -- Developmental origins of health and disease across generations : theory, observation, experiment / M.W. Gillman [and others] -- Early embryo environment and developmental potential / T.P -- Fleming, K.D. Sinclair, K.L. Kind -- Early environmental influences on lung development : implications for lung function and respiratory health throughout life / R. Harding [and others] -- Development of the fetal hypothalamic-pituitary-adrenal-placental axis : implications for postnatal health / J. Challis [and others] -- Developmental origins of musculoskeletal disease / C. Cooper [and others]
Developmental origins of reproductive health / D.M. Sloboda, R. Hart, M. Hickey -- Developmental origins of immune tolerance : pathways and influences / S.L. Prescott -- Developmental programming of the kidney / M.J. Nijland, P.W. Nathanielsz -- Perinatal appetite programming / M. Desai, E. Keen-Rhinehart, M.G. Ross -- Fetal programming of type 2 diabetes / A. Piekarz, S.E. Ozanne -- Developmental origins of diabetes : interventional strategies / R.A. Simmons -- Prenatal risk factors for breast cancer and clues to the underlying biological mechanisms from animal and human studies / R. Troisi, I. dos Santos Silva, R.R. Newbold -- The offspring of women with severe mental disorder / V.A. Morgan [and others] -- Approaches to evaluate gene-environment interactions underlying the developmental origins of health and disease / C.E. Pennell [and others]
Summary A Karger 'Publishing Highlights 1890-2015' title <br />There is compelling evidence that many of the risks leading to the most frequent chronic diseases in adulthood originate in the earliest stages of life. Adverse environmental conditions in utero and during infancy can lead to negative health effects during the subsequent lifetime of the exposed individual. This book offers precious insights into the latest concepts and results from epidemiologic, clinical and basic studies in this burgeoning area of health care. The developmental origins of various diseases such as diabetes, obesity and cancer are examined, as well as the early programming of reproductive health and different organs. Attention is given to the impact of environmental factors such as nutrition and pollution, and the mediating genetic and epigenetic pathways are reviewed. A crucial point under discussion is the concept of environmental insults adversely affecting not only the exposed persons, but also their descendants. In addition, the economic consequences of a suboptimal start to life and the importance of preventive measures are stressed. This publication is of great value to anyone interested in health care, notably to specialists in obstetrics, pediatrics, internal medicine, obesity, diabetes and heart disease
Bibliography Includes bibliographical references and indexes
Notes Print version record
Subject Epidemiology.
Birth weight, Low -- Health aspects
Health risk assessment.
Prenatal influences.
Embryology.
Disease susceptibility.
Embryonic Development
Embryonic and Fetal Development
Epidemiology
Health Status Indicators
Disease Susceptibility
Epigenesis, Genetic
Prenatal Exposure Delayed Effects
Risk Factors
MEDICAL -- Health Risk Assessment.
MEDICAL -- Epidemiology.
Embryology
Disease susceptibility
Epidemiology
Health risk assessment
Prenatal influences
Foetus -- génétique.
Foetus.
Form Electronic book
Author Newnham, John P
Ross, Michael G
LC no. 2009009513
ISBN 9783805591409
3805591403