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Book Cover
E-book
Author Neubert, Reinhard H. H

Title Affinity Capillary Electrophoresis in Pharmaceutics and Biopharmaceutics
Published Hoboken : CRC Press, 2003

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Description 1 online resource (392 pages)
Series Drugs and the Pharmaceutical Sciences
Drugs and the pharmaceutical sciences.
Contents Front Cover; Title Page; Preface; Contents; Chapter 1- Principles of Capillary Electrophoresis; Chapter 2- Theory of Affinity Electrophoresis; Chapter 3- Determination of Physicochemical Parameters; Chapter 4- Affinity of Drugs to Excipients; Chapter 5- Affinity of Drugs to Pharmaceutical Vehicle Systems: Micelles; Chapter 6- Affinity of Drugs to Pharmaceutical Vehicle Systems: Microemulsions; Chapter 7- Interaction of Drugs with Liposomes and Proteoliposomes; Chapter 8- Interactions Between Chiral Drugs and Cyclodextrins
Chapter 9- Affinity of Drugs to Proteins and Protein-Protein InteractionsChapter 10- Affinity Capillary Electrophoresis: DNA Interactions with Peptides, Proteins, and Modified DNA; Chapter 11- Characterization of Polysaccharide Interactions; Chapter 12- Characterization of Immunoreactions; Chapter 13- Hyphenation of Affinity Capillary Electrophoresis with Mass Spectrometry; Chapter 14- Conclusions; Index; Back Cover
Summary This reference presents the most recent breakthroughs and techniques in affinity capillary electrophoresis (ACE) to measure and determine the physicochemical and thermodynamic parameters of drug compounds. The authors offer strategies to explore and characterize interactions between drugs, drug vehicles, and biological membranes to facilitate developments in controlled drug delivery and targeting. The book contains current applications and procedures to identify binding constants between drugs, biological structures, proteins, nucleic acids, and plasmids, increase drug bioavailability, enhance
Notes Print version record
Subject Capillary electrophoresis.
Affinity electrophoresis.
Drugs -- Analysis.
Chemistry, Pharmaceutical -- methods
Electrophoresis, Capillary
Biopharmaceutics -- methods
Combinatorial Chemistry Techniques
Drug Compounding
Affinity electrophoresis
Capillary electrophoresis
Drugs -- Analysis
Kapillarelektrophorese
Pharmazeutische Analyse
Form Electronic book
Author Ruttinger, Hans-Hermann
ISBN 9781135546304
1135546304