| Description |
1 online resource (xvii, 323 pages) : illustrations |
| Contents |
Ch. 1. Introduction. 1.1. Cancer and radiation therapy. 1.2. Historical development of radiation therapy. 1.3. Modern tools for conventional radiotherapy. 1.4. Glossary -- ch. 2. Physical and radiobiological properties of hadrons. 2.1. Basic facts in radiotherapy. 2.2. An introduction to hadrontherapy. 2.3. Energy loss. 2.4. Interaction of hadrons with biological matter -- ch. 3. Status of clinical research in protontherapy. 3.1. Precision in radiotherapy and the role of protons in improving treatment precision. 3.2. Clinical experience in protontherapy. Patient statistics. 3.3. Clinical indications for protontherapy. 3.4. Hadrontherapy diseases categories. 3.5. Number of hadrontherapy patients world-wide -- ch. 4. Hardontherapy facilities world-wide. 4.1. Hadrons acceleration and beam delivery technologies for radiotherapy. 4.2. Historical development of hadrontherapy centers. 4.3. Planned hadrontherapy centers. 4.4. International collaborations for design an universal protontherapy center. 4.5. Firm project of protontherapy centers -- ch. 5. Requirements for hadrontherapy centers. 5.1. Medical and technical performance specifications for the clinical proton beam. 5.2. Performance specification for the general facility. 5.3. Protontherapy equipment system. 5.4. Building design -- ch. 6. Protontherapy accelerators. 6.1. Performance specifications for accelerators systems. 6.2. Operating principles of proton accelerators. 6.3. Examples of cyclotrons for protontherapy. 6.4. Examples of synchrotrons for protontherapy. 6.5. Examples of linear accelerators for protontherapy -- ch. 7. Beam transport and delivery systems. 7.1. Effects of material in the beam path. 7.2. Performance specifications for beam transport system. 7.3. Performance specifications for treatment beam line (nozzle). 7.4. Beam transport systems. 7.5. Beam preparation for clinical use -- ch. 8. Proton gantries. 8.1. Specifications for the proton gantries. 8.2. Proton gantries solutions -- ch. 9. Radiation detectors. 9.1. Dosimetry principles. 9.2. Beam monitoring, dosimetry and microdosimetry. 9.3. Phantoms. 9.4. Dosimetry intercomparisons and protocol for protontherapy beams. 9.5. Examples of monitoring and dosimetry systems. 9.6. Cost estimations -- ch. 10. Treatment ancillary facilities. 10.1. Performance specifications for treatment ancillary facilities. 10.2. Treatment planning software and hardware. 10.3. Patient positioning and alignment devices. 10.4. Systems for irradiation gated by respiration of the patient -- ch. 11. Control system of the protontherapy center. 11.1. Control system of the protontherapy center. 11.2. Control system proposed for Italian hadrontherapy center. 11.3. Safety systems -- ch. 12. Shielding for proton facility. 12.1. Performance specifications for shielding. 12.2. Bunker project for Italian hadrontherapy center -- ch. 13. Global costs and financial analysis of the activities of the proton. 13.1. Cost considerations of hadrontherapy. 13.2. Comparison of treatment costs. 13.3. Global costs of existing the proton facilities -- ch. 14. Proposal of a dedicated protontherapy facility. 14.1. Clinical requirements for a dedicated protontherapy center. 14.2. Conclusions |
| Summary |
Hadronic radiotherapy uses particle beams to treat tumours located near critical body structures and tumours that respond poorly to conventional photon and electron beam radiotherapy. Initial research in hadronic radiotherapy was performed using accelerators built for physics research. The good results of the proton and ion therapy programs have enhanced the tendency to use protontherapy as a routine method. There are about 20 working protontherapy facilities (first, second and third generation) and more than 30 centres are planned. This book presents the first comprehensive overview of the field with a discussion on the fundamental basis of particle physics and radiobiology, as well as review of clinical and technical specifications and designs for proton radiotherapy. In particular, the current designs of proton and heavy ion accelerators, beam delivery systems, gantries, beam monitoring and dosimetry systems, control and safety systems, patient positioning and immobilization devices, and ancillary treatment facilities are widely discussed |
| Bibliography |
Includes bibliographical references (pages 307-317) and index |
| Notes |
English |
|
Print version record |
| Subject |
Proton accelerators.
|
|
Radiotherapy, High energy.
|
|
Particles (Nuclear physics)
|
|
Radiotherapy, High-Energy
|
|
Elementary Particles
|
|
particle physics.
|
|
SCIENCE -- Physics -- Nuclear.
|
|
SCIENCE -- Physics -- Atomic & Molecular.
|
|
Particles (Nuclear physics)
|
|
Proton accelerators
|
|
Radiotherapy, High energy
|
| Form |
Electronic book
|
| Author |
Scharf, Waldemar.
|
| ISBN |
9789812811646 |
|
9812811648 |
|
1281960667 |
|
9781281960665 |
|
9786611960667 |
|
661196066X |
|
