| Description |
1 online resource (xxiv, 502 pages) : illustrations |
| Contents |
Front Matter -- From Milligrams to Tons: The Importance of Synthesis and Process Research in the Development of New Drugs / Martin Karpf -- Design of Dynamic Salt Catalysts Based on Acid-Base Combination Chemistry / Kazuaki Ishihara -- Asymmetric Oxidation with Hydrogen Peroxide, an Effective and Versatile Oxidant / Tsutomu Katsuki -- Development of Palladium Catalysts for Chemoselective Hydrogenation / Hironao Sajiki, Yasunari Monguchi -- Silicon-Based Carbon-Carbon Bond Formation by Transition Metal Catalysis / Yoshiaki Nakao, Tamejiro Hiyama -- Direct Reductive Amination with Amine Boranes / Karl Matos, Elizabeth R Burkhardt -- Industrial Synthesis of Perfluorinated Building Blocks by Liquid-Phase Direct Fluorination / Takashi Okazoe -- Cross-Linked Enzyme Aggregates as Industrial Biocatalysts / Roger A Sheldon -- Application of Whole-Cell Biocatalysts in the Manufacture of Fine Chemicals / Michael Schwarm -- Process Development of Amrubicin Hydrochloride, an Anthracycline Anticancer Drug / Kazuhiko Takahashi, Mitsuharu Hanada -- Process Development of HIV Integrase Inhibitor S-1360 / Toshiro Konoike, Sumio Shimizu -- An Efficient Synthesis of the Protein Kinase C Inhibitor JTT-010 / Takashi Inaba -- Process Development of Oral Carbapenem Tebipenem Pivoxil, TBPM-PI / Takao Abe, Masataka Kitamura -- Some Progress in Organic Synthesis of Pharmaceuticals in China / Delong Liu, Wanbin Zhang -- The Use of Continuous Processing to Make AZD 4407 Intermediates / Andrew S Wells -- Sustainable Processes Based on Enzymes Enabling 100% Yield and 100% ee Concepts / Oliver May -- Development of a Novel Synthetic Method for RNA Oligomers / Tadaaki Ohgi, Junichi Yano -- Process Research with Explosive Reactions / Hiromu Kawakubo -- Scientific Strategy for Optical Resolution by Salt Crystallization: New Methodologies for Controlling Crystal Shape, Crystallization, and Chirality of Diastereomeric Salt / Rumiko Sakurai, Kenichi Sakai -- Development of New Drug and Crystal Polymorphs / Mitsuhisa Yamano -- Development of LIPOzymes Based on Biomembrane Process Chemistry / Hiroshi Umakoshi, Toshinori Shimanouchi, Ryoichi Kuboi -- Matching Chemistry with Chemical Engineering for Optimum Design and Performance of Pharmaceutical Processing / Amit V Mahulkar, Parag R Gogate, Aniruddha B Pandit -- The Integration of Safety, Health, and Environmental Considerations into Process Development / Wesley White, Vyv Coombe, Jonathan Moseley -- Index |
| Bibliography |
Includes bibliographical references and index |
| Notes |
Mode of access: World Wide Web |
| Subject |
Chemical processes.
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Pharmaceutical chemistry.
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Chemistry, Pharmaceutical -- methods.
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Chemistry Techniques, Analytical.
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Drug Discovery.
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Pharmaceutical Preparations -- chemical synthesis.
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Technology, Pharmaceutical -- methods.
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| Form |
Electronic book
|
| Author |
Izawa, Kunisuke.
|
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Konoike, Toshiro.
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Shioiri, Takayuki.
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Wiley InterScience (Online service)
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| ISBN |
3527633677 (electronic bk.) |
|
9783527633678 (electronic bk.) |
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