| Description |
1 online resource (436 pages) : illustrations |
| Contents |
Tumor Microenvironment; Contents; Preface; List of Contributors; 1 The Microenvironment in Cancer; 2 Establishing the Tumor Microenvironment; 3 Contributions of the Extracellular Matrix to Tumorigenesis; 4 Matrix Metalloproteinases and Their Inhibitors -- Friend or Foe; 5 Role of Tumor-Associated Macrophages (TAM) in Cancer Related Inflammation; 6 Bone Marrow Stroma and the Leukemic Microenvironment; 7 Microenvironment Factors Influencing Skeletal Metastases; 8 Premetastatic Niches; 9 Hypoxia, Anerobic Metabolism, and Interstitial Hypertension; 10 Hypoxia and the DNA Damage Response |
| Summary |
The microenvironment in which a tumor originates plays a critical role in its initiation and progression. Tumor Microenvironment reviews the importance of tumor microenvironment in cancer management. Particular emphasis is placed on discussing how the unique characteristics of the tumor microenvironment not only impact disease progression and response to conventional anticancer therapies, but have also led to the identification of potential new therapeutic targets and treatment possibilities for cancer patients |
| Bibliography |
Includes bibliographical references and index |
| Notes |
Print version record |
| Subject |
Cancer cells.
|
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Carcinogenesis.
|
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Tumor Microenvironment
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Carcinogenesis
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MEDICAL -- Oncology.
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HEALTH & FITNESS -- Diseases -- Cancer.
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Cancer cells
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Carcinogenesis
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| Form |
Electronic book
|
| Author |
Siemann, Dietmar W.
|
| ISBN |
9780470669808 |
|
0470669802 |
|
9780470669891 |
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0470669896 |
|
