Title Structural and catalytic roles of metal ions in RNA / edited by Astrid Sigel, Helmut Sigel, and Roland K.O. Sigel

Published Cambridge, U.K. : Royal Society of Chemistry, 2011

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Description 1 online resource (xxxi, 391 pages) : illustrations Series Metal ions in life sciences ; v. 9 Metal ions in life sciences ; v. 9. Contents I-iv; v-vi; vii-x; xi-xvi; xvii-xx; xxi-xxii; xxiii-xxxii; 1-36; 37-100; 101-124; 125-140; 141-174; 175-196; 197-234; 235-252; 253-276; 277-298; 299-346; 347-378; 379-392 Summary The discovery of ribozymes triggered a huge interest in the chemistry and biology of RNAs. Much of the recently made progress focusing on metal ions is addressed in Volume 9. This book, written by 28 internationally recognized experts, provides a most up-to-date view and it is thus of special relevance for colleagues teaching courses in biological inorganic chemistry and for researchers dealing, e.g., with nucleic acids, gene expression, and enzymology, but also for those in analytical and bioinorganic chemistry or biophysics. Structural and Catalytic Roles of Metal Ions in RNA describes metal ion-binding motives, methods to detect and characterize metal ion binding sites, and the role of metal ions in folding and catalysis. It deals with diffuse metal ion binding, RNA quadruplexes, the regulation of riboswitches, metal ions and ribozymes, including artificial ribozymes. The ribosome, ribozymes and redox cofactors, as well as the binding of kinetically inert metal ions to RNA are also considered Bibliography Includes bibliographical references and index Notes Online resource; title from title screen (viewed on May 13, 2011) Subject Metal ions. Catalytic RNA. Non-coding RNA. Inorganic compounds. Ions. Molecular structure. Enzymes. Electrolytes. Documentation. RNA. Information services. Nucleic acids. Metals. Anions. Binding sites (Biochemistry) RNA, Untranslated Genetic Structures Molecular Sequence Data Inorganic Chemicals Ions Molecular Structure Enzymes Electrolytes Genetic Phenomena Chemicals and Drugs Documentation RNA Biochemical Phenomena Enzymes and Coenzymes Phenomena and Processes Chemical Phenomena Information Services Nucleic Acids Nucleic Acids, Nucleotides, and Nucleosides Information Science Metals RNA, Catalytic Base Sequence Anions Binding Sites molecular structure. enzyme. documentation (activity) documentation centers. information services. metal. SCIENCE -- Chemistry -- Physical & Theoretical. RNA Nucleic acids Non-coding RNA Molecular structure Metals Ions Inorganic compounds Information services Enzymes Electrolytes Documentation Binding sites (Biochemistry) Anions Catalytic RNA Metal ions Form Electronic book Author Sigel, Astrid. Sigel, Helmut. Sigel, Roland K. O. ISBN 9781849732512 1849732515

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