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Author Pozharskiń≠, A. F. (Aleksandr Fedorovich)

Title Heterocycles in life and society : an introduction to heterocyclic chemistry, biochemistry and applications / Alexander F. Pozharskii, Alan R. Katritzky, Anatoli Soldatenkov
Edition Second edition
Published Chichester, West Sussex : Wiley, 2011
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Description 1 online resource (xi, 382 pages) : illustrations
Contents Heterocycles in Life and Society; Contents; Preface to Second English Edition; Preface to First English Edition; 1. Molecular Rings Studded With Jewels; 1.1 From Homocycle to Heterocycle; 1.2 Building Heterocycles From Benzene; 1.3 Some More Kinds of Heterocycles; 1.4 Problems; 1.5 Suggested Reading; 2. Why Nature Prefers Heterocycles; 2.1 Reactions for all Tastes; 2.2 Heterocycles as Acids and Bases; 2.3 Heterocycles and Metals; 2.4 'There are Subtle Ties of Power. . .'; 2.4.1 The van der Waals-London Interactions; 2.4.2 Hydrogen Bonding; 2.4.3 Electrostatic Interactions
2.4.4 Molecular Complexes2.4.5 Hydrophobic Forces; 2.5 Tautomerism: Heterocycles and Their 'Masks'; 2.6 Problems; 2.7 Suggested Reading; 3. Heterocycles and Hereditary Information; 3.1 Nucleic Acids; 3.2 The Double Helix; 3.3 How One DNA Doubles Itself; 3.4 Protein Synthesis, Genetic Code and the Genome; 3.5 What are Mutations?; 3.6 Mysterious Telomeres; 3.7 Gene Expression; 3.8 Problems; 3.9 Suggested Reading; 4. Enzymes, Coenzymes and Vitamins; 4.1 Molecular Robots; 4.2 Coenzymes and Enzymes as 'Joint Molecular Ventures'; 4.2.1 Oxidative-Reductive Coenzymes
4.2.2 Coenzymes as Carriers of Molecular Species4.3 Vitamins, the 'Molecules of Health'; 4.4 Ribozymes: Vestiges of an Ancient World; 4.5 Problems; 4.6 Suggested Reading; 5. Heterocycles and Bioenergetics; 5.1 ATP as the Universal Currency of Energy; 5.2 Breathing; 5.2.1 Glycolysis; 5.2.2 The Krebs Cycle, or the 'Molecular Merry-Go-Round'; 5.2.3 The Respiratory Chain; 5.3 Problems; 5.4 Suggested Reading; 6. Heterocycles and Photosynthesis; 6.1 Chlorophyll: Sunlight-Receiving Antenna and Energy Carrier; 6.2 What Daylight can Achieve; 6.3 Photosynthesis Without Light; 6.4 Problems
6.5 Suggested Reading7. Heterocycles and Health; 7.1 Medicines From a Natural Storehouse; 7.2 Heterocycles Versus Infectious Microbes; 7.2.1 In Search of 'Magic Bullets'; 7.2.2 Sulfanilamides and Heterocycles; 7.2.3 Antibiotics; 7.2.4 Antibiotics From the Ocean's Depths; 7.2.5 Heterocyclic Antifungal Agents; 7.2.6 Heterocycles Against Parasitic Diseases; 7.3 Heterocycles and Viral Infections; 7.4 Heterocycles and the Diseases of Our Century; 7.4.1 Heterocycles to Cure Stress, Brain Disorders and Pain; 7.4.2 Heterocycles and Cardiovascular Diseases; 7.4.3 Heterocycles and Malignant Tumors
7.5 Heterocyclic Molecules in Combat with Ulcers and Sexual Dysfunctions7.6 Problems; 7.7 Suggested Reading; 8. Heterocycles in Agriculture; 8.1 A Century of Chemical Warfare Against Weeds; 8.2 Regulators of Plant Growth; 8.3 The Struggle Against Voracious Insects; 8.4 Resisting the Kingdoms of Mustiness and Rot; 8.5 Heterocycles in Animal Husbandry; 8.6 Combinatorial Chemistry and Functional Genomics in the Synthesis of Biologically Active Heterocyclic Compounds; 8.7 Problems; 8.8 Suggested Reading; 9. Heterocycles in Industry and Technology; 9.1 Heterocycles and Natural Colors; 9.2 Dyes
Summary "Heterocycles in Life and Society is an introduction to the chemistry of heterocyclic compounds, focusing on their origin and occurrence in nature, biochemical significance and wide range of applications. Written in a readable and accessible style, the book takes a multidisciplinary approach to this extremely important area of organic chemistry. Topics covered include an introduction to the structure and properties of heterocycles; the key role of heterocycles in important life processes such as the transfer of hereditary information, how enzymes function, the storage and transport of bioenergy, and photosynthesis; applications of heterocycles in medicine, agriculture and industry; heterocycles in supramolecular chemistry; the origin of heterocycles on primordial Earth; and how heterocycles can help us solve 21st century challenges. For this second edition, Heterocycles in Life and Society has been completely revised and expanded, drawing on a decade of innovation in heterocyclic chemistry. The new edition includes discussions of the role of heterocycles in nanochemistry, green chemistry, combinatorial chemistry, molecular devices and sensors, and supramolecular chemistry. Impressive achievements include the creation of various molecular devices, the recording and storage of information, the preparation of new organic conductors, and new effective drugs and pesticides with heterocyclic structures. Much new light has been thrown on various life processes, while the chemistry of heterocycles has expanded to include new types of heterocyclic structures and reactions, and the use of heterocyclic molecules as ionic liquids and proton sponges. Heterocycles in Life and Society is an essential guide to this important field for students and researchers in chemistry, biochemistry, and drug discovery, and scientists at all levels wishing to expand their scientific horizon."-- Provided by publisher
"The book takes a multidisciplinary approach to this extremely important area of organic chemistry"-- Provided by publisher
Bibliography Includes bibliographical references and index
Subject Chemistry, Organic.
Heterocyclic chemistry.
Form Electronic book
Author Katritzky, Alan R.
Soldatenkov, A. T. (Anatoliń≠ Timofeevich)
LC no. 2010054024
ISBN 1119998387 (electronic bk.)
9781119998389 (electronic bk.)