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Title Behavioral neurobiology of alcohol addiction / Wolfgang H. Sommer, Rainer Spanagel, editors
Published Berlin ; New York : Springer, [2013]
©2013
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Description 1 online resource
Series Current topics in behavioral neurosciences, 1866-3370 ; 13
Current topics in behavioral neurosciences ; 13
Contents Theoretical Frameworks and Mechanistic Aspects of Alcohol Addiction: Alcohol Addiction as a Reward Deficit Disorder / George F. Koob -- Synaptic Effects Induced by Alcohol / David M. Lovinger and Marisa Roberto -- Signaling Pathways Mediating Alcohol Effects / Dorit Ron and Robert O. Messing -- Neurocircuitry Involved in the Development of Alcohol Addiction: The Dopamine System and its Access Points / Bo Söderpalm and Mia Ericson -- What is in that Drink: The Biological Actions of Ethanol, Acetaldehyde, and Salsolinol / Gerald A. Deehan Jr., Mark S. Brodie and Zachary A. Rodd -- Modeling the Diagnostic Criteria for Alcohol Dependence with Genetic Animal Models / John C. Crabbe, Kenneth S. Kendler and Robert J. Hitzemann -- Non-Human Primate Models of Alcohol-Related Phenotypes: The Influence of Genetic and Environmental Factors / Christina S. Barr -- Genetically Selected Alcohol Preferring Rats to Model Human Alcoholism / Roberto Ciccocioppo
Advanced Transgenic Approaches to Understand Alcohol-Related Phenotypes in Animals / Ainhoa Bilbao -- Modeling Alcohol Self-Administration in the Human Laboratory / Ulrich S. Zimmermann, Sean O'Connor and Vijay A. Ramchandani -- Animal Models of Excessive Alcohol Consumption in Rodents / Howard C. Becker -- Modeling Relapse Situations in the Human Laboratory / Rajita Sinha -- Modeling Relapse in Animals / Rémi Martin-Fardon and Friedbert Weiss -- Invertebrate Models of Alcoholism / Henrike Scholz and Julie A. Mustard -- The Dopamine System in Mediating Alcohol Effects in Humans / K. Charlet, A. Beck and A. Heinz -- Stimulant and Sedative Effects of Alcohol / Reuben A. Hendler, Vijay A. Ramchandani, Jodi Gilman and Daniel W. Hommer -- Chronic Alcohol Consumption, Abstinence and Relapse: Brain Proton Magnetic Resonance Spectroscopy Studies in Animals and Humans / Dieter J. Meyerhoff, Timothy C. Durazzo and Gabriele Ende
Translational Approaches to Medication Development / Selena Bartlett and Markus Heilig -- New Pharmacological Treatment Strategies for Relapse Prevention / Rainer Spanagel and Valentina Vengeliene -- The Challenge of Studying Parallel Behaviors in Humans and Animal Models / David N. Stephens, Hans S. Crombag and Theodora Duka -- A Translational Approach to Novel Medication Development for Protracted Abstinence / Barbara J. Mason and Amanda E. Higley -- New Approaches to Addiction Treatment Based on Learning and Memory / Falk Kiefer and Christina Dinter -- Adolescent Substance Misuse: Neurobiology and Evidence-Based Interventions / Nicola C. Newton, Maeve O'Leary-Barrett and Patricia J. Conrod -- Deep Brain Stimulation as a Therapy for Alcohol Addiction / Thomas F. Münte, Hans-Jochen Heinze and Veerle Visser-Vandewalle
Summary The question of how alcohol alters mood states and why this may end up becoming an addiction has puzzled alcohol researchers for decades. In this volume, a group of highly distinguished experts and leaders in alcohol addiction research presents our current state of knowledge and remaining research challenges, as well as interesting viewpoints on future research directions aimed to stimulate communication and convergence between clinical and preclinical researchers, and to renew interest in the vibrant field of alcohol addiction research among a broad scientifically minded audience. Five Current Topics are discussed in this volume: Neurobiological mechanisms of alcoholism, Genetics, Clinical phenotypes and their preclinical models, Brain imaging, and Translational approaches for treatment development, both pharmacological and non-pharmacological. These areas have in our opinion substantially brought alcohol research forward and influenced our thinking about how to reach our common paramount goal, namely to offer effective treatment solutions for an extensive group of patients with largely unmet medical needs
Analysis Medicine
Neurosciences
Psychiatry
Psychopharmacology
Biomedicine
Bibliography Includes bibliographical references
Subject Alcoholism -- Psychological aspects.
Neurosciences.
Alcohol -- Physiological effect.
Alcohol-Related Disorders -- genetics.
Alcohol-Related Disorders -- physiopathology.
Dopamine.
Neurobiology.
Form Electronic book
Author Sommer, Wolfgang H.
Spanagel, R. (Rainer), 1961-
LC no. 2012942257
ISBN 9783642287206 (electronic bk.)
3642287204 (electronic bk.)
3642287190
9783642287190