| Description |
1 online resource |
| Series |
Chemical analysis : a series of monographs on analytical chemistry and its applications ; volume 185 |
|
Chemical analysis ; v. 185.
|
| Contents |
Background -- Chemical measurement systems and their errors -- The response, net response and content domains -- Traditional limits of detection -- Modern limits of detection -- Receiver operating characteristics -- Statistics of an ideal model CMS -- If only the true intercept is unknown -- If only the true slope is unknown -- If the true intercept and true slope are both unknown -- If only the population standard deviation is unknown -- If only the true slope is known -- If only the true intercept is known -- If all three parameters are unknown -- Bootstrapped detection limits in a real CMS -- Four relevant considerations -- Neyman-Pearson hypothesis testing -- Heteroscedastic noises -- Limits of quantitation -- The sampled step function -- The sampled rectangular pulse -- The sampled triangular pulse -- The sampled Gaussian pulse -- Parting considerations |
| Summary |
Details methods for computing valid limits of detection.-Clearly explains analytical detection limit theory, thereby mitigating incorrect detection limit concepts, methodologies and results -Extensive use of computer simulations that are freely available to readers -Curated short-list of important references for limits of detection -Videos, screencasts, and animations are provided at an associated website, to enhance understanding -Illustrated, with many detailed examples and cogent explanations |
| Bibliography |
Includes bibliographical references and index |
| Notes |
Print version record and CIP data provided by publisher |
| Subject |
Analytical chemistry.
|
|
chemical analysis.
|
|
SCIENCE -- Chemistry -- Analytic.
|
|
Analytical chemistry.
|
| Form |
Electronic book
|
| LC no. |
2017005375 |
| ISBN |
9781523114948 |
|
1523114940 |
|
9781119188971 |
|
1119188970 |
|
