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Title Neuroactive steroids in brain function, behavior and neuropsychiatric disorders : novel strategies for research and treatment / Michael S. Ritsner, Abraham Weizman, editors
Published [New York?] : Springer, [2008]
Online access available from:
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Description 1 online resource (xx, 559 pages) : illustrations
Contents Neurosteroid : molecular mechanisms of action on the GABA[subscript A] receptor / Ming-De Wang [and others] -- Steroid metabolism in glial cells / Roberto C. Melcangi and Luis M. Garcia-Segura -- Involvement of neuroactive steroids in hippocampal disorders : lessons from animal models / Alejandro F. De Nicola [and others] -- Estrogen modulation of visceral nociception / Victor V. Chaban -- Neuroactive steroids : effects on cognitive functions / Torbjörn Bäckström [and others] -- Estrogen, cholinergic system and cognition / Sonsoles de Lacalle, Bryan Hyler, and Thomas Borowski -- Local production of estrogen and its rapid modulatory action on synaptic plasticity / Sugur Kawato [and others] -- Effects of estradiol and DHEA on morphological synaptic plasticity / Tibor Hajszan [and others] -- Pregnane steroids and short-term neural plasticity / Yuri B. Saalmann and Mike B. Calford -- Steroidogenesis and neuroplasticity in the songbird brain / Colin J. Saldanha and Barney A. Schlinger -- Dehydroepiandrosterone, as endogenous inhibitor of neuronal cell apoptosis : potential therapeutic implications in neurodegenerative diseases / Ioannis Charalampopoulos [and others] -- DHEA and DHEA-S, and their functions in the brain and adrenal medulla / Alexander W. Krug, Christian G. Ziegler, and Stefan R. Bornstein -- Neurosteroids in the aging brain / Rael D. Strous -- Dehydroepiandrosterone and pregnenolone alterations in schizophrenia / Michael S. Ritsner [and others] -- Neurosteroids in cortical development and the etiology of schizophrenia / Samantha S. Gizerian -- Neurosteroid perturbation and neuropsychiatric symptoms in schizophrenia : from the mechanisms to the treatment / Flavia di Michele, Carlo Caltagirone, and Gianfranco Spalletta -- Dehydroepiandrosterone administration in treating medical and neuropsychiatric disorders : high hopes, disappointing results, and topics for future research / Michael S. Ritsner
Summary "This book provides an overview of the role of neurosteroids and neuroactive steroids, such as pregnenolone and dehydroepiandrosterone, allopregnanolone, progesterone and others in the regulation of brain processes and neuropsychiatric disorders. The book addresses the neurosteroid function in brain development and plasticity, in both the normal and the pathological brain including the aging brain, cognitive functioning, response to stress, anxiety and mood disorders, schizophrenia, and Alzheimer's disease. It also suggests possible therapeutic approaches to the use of natural occurring or sinthetic neurosteroids. This book offers a review of these bioactive molecules that is relevant to a broad readership which includes neuroscientists, psychiatrists, neurologists, endocrinologists, pharmacologists, clinical psychologists, general practitioners, geriatricians, graduate students in neuroscience, and health care providers in the field of mental health and neurology."--Jacket
Bibliography Includes bibliographical references and index
Notes Print version record
Subject Neuroendocrinology.
Steroid hormones.
Brain -- drug effects.
Mental Disorders -- drug therapy.
Neuronal Plasticity -- drug effects.
Steroids -- pharmacology.
Steroids -- physiology.
Form Electronic book
Author Ritsner, Michael S.
Weizman, Abraham.
ISBN 1402068549