| Description |
1 online resource (xiv, 328 pages) : illustrations |
| Contents |
Optimal Pairwise Alignment -- Biological Sequences and the Exact String Matching Problem -- Fast Alignments: Genome Comparisons and Database Searches -- Multiple Sequence Alignment -- Sequence Profiles and Hidden Markov Models -- Gene Prediction -- Phylogeny -- Sequence Variation and Molecular Evolution -- Genes in Populations: Forward in Time -- Genes in Populations: Backward in Time -- Testing Evolutionary Hypotheses |
| Summary |
"This introduction to computational biology is centered on the analysis of molecular sequence data. There are two closely connected aspects to biological sequences: (i) their relative position in the space of all other sequences, and (ii) their movement through this sequence space in evolutionary time. Accordingly, the first part of the book deals with classical methods of sequence analysis: pairwise alignment, exact string matching, multiple alignment, and hidden Markov models. In the second part evolutionary time takes center stage and phylogenetic reconstruction, the analysis of sequence variation, and the dynamics of genes in populations are explained in detail. In addition, the book contains a computer program with a graphical user interface that allows the reader to experiment with a number of key concepts developed by the authors."--Jacket |
| Bibliography |
Includes bibliographical references (pages 299-311)-and indexes |
| Notes |
Master and use copy. Digital master created according to Benchmark for Faithful Digital Reproductions of Monographs and Serials, Version 1. Digital Library Federation, December 2002. http://purl.oclc.org/DLF/benchrepro0212 MiAaHDL |
|
English |
|
digitized 2011 HathiTrust Digital Library committed to preserve pda MiAaHDL |
| In |
Springer e-books |
| Subject |
Computational biology.
|
|
Bioinformatics.
|
|
Sequence Analysis
|
|
Computational Biology
|
|
Computational Biology -- methods
|
|
Genomics -- methods
|
|
Molecular Sequence Data
|
|
Sequence Analysis.
|
|
Computational Biology -- methods.
|
|
Genomics -- methods.
|
|
Molecular Sequence Data.
|
|
Bio-informatique.
|
|
Computational Biology.
|
|
Biomédecine.
|
|
Sciences de la vie.
|
|
Bioinformatics
|
|
Computational biology
|
|
Molekulare Bioinformatik
|
| Form |
Electronic book
|
| Author |
Wiehe, Thomas
|
| ISBN |
3764367008 |
|
9783764367008 |
|
9783764373870 |
|
3764373873 |
|
1281350141 |
|
9781281350145 |
|
