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Title The molecular and cellular basis of neurodegenerative diseases : underlying mechanisms / edited by Michael S. Wolfe
Published London : Academic Press is an imprint of Elsevier, [2018]
©2018
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Description 1 online resource
Contents Front Cover; The Molecular and Cellular Basis of Neurodegenerative Diseases; Copyright Page; Dedication; Contents; List of Contributors; Preface; 1 Solving the Puzzle of Neurodegeneration; Introduction: The General Problem of Neurodegeneration; Epidemiology and Clinical Presentation; Molecular Pathology; Genetics; Molecular Clues to Mechanisms of Pathogenesis; Common Themes and Controversies in Neurodegeneration; Animal Models; Prospects for Therapeutics; Conclusions and Perspective; References; 2 Prion Diseases; Introduction and Historical Perspective
Summary The Molecular and Cellular Basis of Neurodegenerative Diseases: Underlying Mechanisms presents the pathology, genetics, biochemistry and cell biology of the major human neurodegenerative diseases, including Alzheimer's, Parkinson's, frontotemporal dementia, ALS, Huntington's, and prion diseases. Edited and authored by internationally recognized leaders in the field, the book's chapters explore their pathogenic commonalities and differences, also including discussions of animal models and prospects for therapeutics. Diseases are presented first, with common mechanisms later. Individual chapters discuss each major neurodegenerative disease, integrating this information to offer multiple molecular and cellular mechanisms that diseases may have in common. This book provides readers with a timely update on this rapidly advancing area of investigation, presenting an invaluable resource for researchers in the field
Bibliography Includes bibliographical references and index
Notes Online resource; title from PDF title page (EBSCO, viewed April 6, 2018)
Subject Nervous system -- Degeneration -- Molecular aspects.
Neurodegenerative Diseases -- microbiology.
Form Electronic book
Author Wolfe, Michael S., editor
ISBN 0128113057 (electronic bk.)
9780128113059 (electronic bk.)