| Description |
1 online resource |
| Contents |
Intro; Preface; Contents; Contributors; Including Toxicity Risk in Balanced Clinical Decision Making; References; Acute and Late Skin Toxicity from Breast Radiation; The Layers of Skin and Anatomy of the Breast; Composition of the Skin; Breast Anatomy; Radiotherapy-Related Skin Toxicity in Breast Cancer; General Principals of the Radiation Response and Breast-Specific Considerations; Acute Skin Toxicities; Diagnosis and Grading of Acute Skin Toxicity; Clinical Findings of Acute Radiation Toxicity; Erythema; The Desquamation Continuum; Late Skin Toxicity |
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Diagnosis and Grading of Late Skin ToxicityTypes of Late Skin Toxicity; Radiation-Induced Fibrosis; Atrophy; Hyperpigmentation; Telangiectasia; Morphea; Radiation Recall; Risk Factors for Acute and Late Radiation Skin Toxicity; Patient Predisposition to Skin Toxicity; Patient Characteristics; Genetic Predisposition via Altered DNA Damage Repair; Dysfunctional Immune Response; Radiation Delivery and Planning Risk Factors; Other Non-radiation Treatment Characteristics; Management of Acute and Late Skin Toxicity; Management of Acute Toxicity; Prevention of Acute Skin Toxicity |
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Treatment of Acute Skin ToxicityTreatment of Late Toxicity; Considerations for Including Risk of Toxicity in Management Decisions; Conclusions and Future Directions; References; Fatigue Associated with Radiation Treatment for Breast Cancer; Introduction; Fatigue Prevalence During and After Breast Cancer Radiotherapy; Prevalence of Fatigue; Fatigue Severity; Fatigue Scales; Biological Mechanisms of Fatigue; Inflammation; Inflammation and Radiotherapy-Induced Dermatitis; Cellular Immunity; Anemia; Predictors of Fatigue; Demographic Factors; Clinical, Tumor, and Treatment-Related Factors |
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Behavioral SymptomsRadiation Dose, Fractionation, and Fatigue; Treatments for Fatigue; References; Pain Associated with Radiation Treatment for Breast Cancer; Introduction; Epidemiology of Pain; Etiology and Pathophysiology of Pain; Acute Pain; Prevalence and Incidence; Symptoms and Pain Location; Risk Factors; Chronic Persistent Pain; Prevalence; Risk Factors; Delayed Radiation-Induced Brachial Plexus Neuropathy (RIBPN); Incidence/Prevalence; Symptoms; Risk Factors; Assessment of Pain; Unidimensional Pain Scale; Multidimensional Pain Assessment; Neuropathic Pain (NP) Assessment |
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Management of PainAcute and Chronic Persistent Pain; The WHO Analgesic Ladder; Non-pharmacological Strategies; Neuropathic Pain (NP); Radiation-Induced Brachial Plexus Neuropathy (RIBPN); Risk Reduction; Pain Management; Conclusion; References; Considerations for Post-Mastectomy Radiation Therapy in the Setting of Breast Reconstruction; Introduction; Surgical Factors Impacting PMRT Outcomes; Patient Factors Impacting PMRT Outcomes; Radiation Planning Factors; Conclusion; References; Lymphedema After Breast Cancer Treatment; Incidence of BCRL; Detection of BCRL and Diagnostic Methods |
| Summary |
This book is a comprehensive guide to breast toxicity. Adjuvant radiation remains standard for a majority of women who undergo breast-conserving surgery for breast cancer, and indications for post-mastectomy and regional lymph node irradiation have also broadened with recent publications. At the same time, locoregional recurrence has declined and survival has improved in recent decades. In the current era of excellent breast cancer outcomes, then, considering the balance between toxicity and outcomes becomes paramount. Several recent editorials recommend considering toxicity against the potential benefit of adjuvant radiation in tailoring radiation decisions for individual patients. Thus, a clear understanding of the potential toxicities of adjuvant radiation for breast cancer is critical to optimizing outcomes in modern breast cancer management. Here, authors have collected recent data focused on toxicity of treatment that provide an opportunity for improving this optimization. Chapters cover both acute and late toxicity of radiation for breast cancer, including tailored risk assessment for each of these potential toxicities, considerations for including risk of toxicity in management decisions, and toxicity management strategies. This is an ideal guide for radiation oncologists, residents, and oncologists seeking to optimize care for their patients |
| Bibliography |
Includes bibliographical references and index |
| Notes |
Online resource; title from PDF title page (EBSCO, viewed March 20, 2019) |
| Subject |
Cancer -- Radiotherapy.
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Radiotherapy -- Toxicology
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Radiation Oncology
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MEDICAL -- Pharmacology.
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Cancer -- Radiotherapy
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| Form |
Electronic book
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| Author |
Wright, Jean L., editor
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| ISBN |
9783030116200 |
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3030116204 |
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9783030116217 |
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3030116212 |
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