| Description |
1 online resource (747 pages) |
| Series |
Drugs and the Pharmaceutical Sciences Ser |
|
Drugs and the Pharmaceutical Sciences Ser
|
| Contents |
Cover; Half Title; Title Page; Copyright Page; Table of Contents; Preface; Editors; Contributors; 1: Introduction; Section I: Discovery; 2: Physiology of the Airways; 3: Drug Targeting to the Lung: Chemical and Biochemical Considerations; Section II: Aerosol Critical Attributes; 4: Aerosol Physics and Lung Deposition Modeling; 5: Practical Aspects of Imaging Techniques Employed to Study Aerosol Deposition and Clearance; 6: Pharmacokinetics and Pharmacodynamics of Drugs Delivered to the Lung; Section III: Active Pharmaceutical Ingredient/Drug Product Manufacturing |
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7: Small Molecules: Process Intensification and Continuous Synthesis8: Biologic Drug Substance and Drug Product Manufacture; 9: Scale-Up Considerations for Orally Inhaled Drug Products; 10: Quality by Control; Section IV: Particle Engineering/Processing; 11: Milling and Blending: Producing the Right Particles and Blend Characteristics for Dry Powder Inhalation; 12: Engineering Stable Spray-Dried Biologic Powder for Inhalation; 13: Supercritical Fluid Manufacture; 14: Particle Engineering Technology for Inhaled Therapies; Section V: Drug Product Formulation |
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15: Emerging Pulmonary Delivery Strategies in Gene Therapy: State of the Art and Future Considerations16: Genome Editing for Genetic Lung Diseases; 17: Inhalation Drug Products Containing Nanomaterials; Section VI: Devices; 18: Pressurized Metered-Dose Inhalers; 19: Dry Powder Inhalation; 20: Nebulizers; 21: Soft Mist Inhalers; Section VII: Drug Product Testing; 22: Quality by Design Considerations; 23: Solid State Testing of Inhaled Formulations; 24: Aerodynamic Particle Size Testing; Section VIII: Regulatory Considerations |
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25: Scanning the Intricate Regulatory Landscape and Trying to Peek Over the Horizon26: Pharmacopeial and Regulatory Guidances on Product Quality and Performance; 27: The European Union Regulatory Scene; Section IX: Preclinical Testing; 28: Reconstituted 2D Cell and Tissue Models; 29: 3D In Vitro/Ex Vivo Systems; 30: Preclinical Models for Pulmonary Drug Delivery; Section X: Clinical Testing; 31: Bioequivalence of Orally Inhaled Drug Products: Challenges and Opportunities; 32: General Conclusions; Index |
| Notes |
Print version record |
| Subject |
Aerosol therapy.
|
|
Aerosol therapy
|
| Form |
Electronic book
|
| Author |
Da Rocha, Sandro R
|
| ISBN |
9780429621710 |
|
042962171X |
|
