Introductory -- The development of the hot condition -- The development of the cold condition -- The significance of the changes observed in the state of the circulation -- Redistribution of internal heat after exposure to cold -- Equilibration of loss and production of heat -- Further observations on the pulse-rate -- Observations made with the body immersed in water -- Reflex acceleration of the pulse-rate by cold and hot water in motion -- Critical changes of the circulation in a varying thermal environment -- Conclusion