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Author Grady, Christine.

Title The search for an AIDS vaccine : ethical issues in the development and testing of a preventive HIV vaccine / Christine Grady
Published Bloomington, Ind. : Indiana University Press, [1995]
©1995
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Description 1 online resource (193 pages)
Series Medical ethics series
Medical ethics series.
Contents Vaccines and their development: historical, social, and scientific perspectives -- Human-subjects research and the regulation of drugs and biologicals -- Human-subjects research and HIV vaccines -- The state of HIV vaccine science -- Planning phase III HIV vaccine efficacy trials -- Summary
Summary Efforts to halt the spread of AIDS have failed so far, and the creation of a vaccine seems the best hope for controlling the disease. Yet the process of developing and testing an HIV vaccine raises a host of difficult ethical issues. Describing the role of vaccines in controlling infectious disease, this study surveys the guidelines, regulations, and attitudes concerning human-subjects research. There is current information on the state of HIV research and the challenges facing scientists. Vaccine research differs considerably from drug research, and Grady explores the current wisdom governing research with human subjects. Proposing a model for the ethical conduct of vaccine research in general, this book applies it to the complex case of an HIV vaccine. Clinical trials are already ongoing, and the next step, field trials to determine efficacy, involves another set of issues - and a call for new strategies for ethical conduct. The Search for an AIDS Vaccine is essential reading for everyone interested in ethics and the conduct of HIV vaccine research
Bibliography Includes bibliographical references (pages 163-185) and index
Notes Print version record
Subject AIDS (Disease) -- Prevention -- Moral and ethical aspects.
AIDS (Disease) -- Research -- Moral and ethical aspects.
AIDS (Disease) -- Vaccination -- Moral and ethical aspects.
Clinical trials -- Moral and ethical aspects.
AIDS Vaccines.
Clinical Trials as Topic.
Ethics, Medical.
HIV Infections -- prevention & control.
Research.
Form Electronic book
ISBN 0585257604 (electronic bk.)
9780585257600 (electronic bk.)