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Title Biochemical basis and therapeutic implications of angiogenesis / Jawahar L. Mehta, Naranjan S. Dhalla, editors
Published New York ; London : Springer, 2013
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Description 1 online resource
Series Advances in biochemistry in health and disease ; v. 6
Advances in biochemistry in health and disease ; v. 6
Contents Molecular Mechanisms of Angiogenesis. Endothelial Growth Factor Receptors in Angiogenesis / David J. Bruce, Peng H. Tan -- Role of Transforming Growth Factor Beta in Angiogenesis / Alicia Viloria-Petit [and others] -- Role of Cytokines in Angiogenesis: Turning It On and Off / Melissa A. Thal, Raj Kishore -- Neuropeptides and Angiogenesis / Leena Pradhan-Nabzdyk, Christoph Nabzdyk -- Role of Integrins in Angiogenesis / Ghazaleh Tabatabai, Michael Weller -- Regulation of Angiogenesis by Hypoxia-Inducible Factors / Hideki Hayakawa, Futoshi Shibasaki -- Role of Mast Cells in Angiogenesis / Enrico Crivellato, Domenico Ribatti -- Vascular Stem Cells in Regulation of Angiogenesis / Jingwei Lu, Vincent J. Pompili, Hiranmoy Das -- Toll-Like Receptor-Linked Signal Transduction in Angiogenesis / Karsten Grote, Harald Schütt, Bernhard Schieffer -- Role of Sex Steroids in Angiogenesis / Laura Lecce, Yuen Ting Lam, Martin K.C. Ng -- Biochemical Mechanisms of Exercise-Induced Angiogenesis / Dustin Scott Kehler, Naranjan S. Dhalla, Todd A. Duhamel
Pathophysiological Aspects of Angiogenesis. Angiogenesis in Atherosclerosis: An Overview / Sadip Pant, Abhishek Deshmukh, Jawahar L. Mehta -- Role of Serotonin in Angiogenesis in Diabetes / Masaaki Iwabayashi [and others] -- Brain Angiogenesis After Stroke / Kazuhide Hayakawa [and others] -- Angiogenesis in Myocardial Ischemia / Yasuyuki Fujita, Takayuki Asahara, Atsuhiko Kawamoto -- Adipose Tissue-Derived Mesenchymal Stem Cell and Angiogenesis in Ischemic Heart Disease / Lina Badimon, Blanca Oñate, Gemma Vilahur -- Trials of Angiogenesis Therapy in Patients with Ischemic Heart Disease / Sandeep Singla, Jawahar L. Mehta -- Angiogenesis in Cancer / Gerald W. Prager, Christoph C. Zielinski -- Potential Mechanisms Linking Oxidized LDL to Susceptibility to Cancer / Magomed Khaidakov, Jawahar L. Mehta -- Role of Genetic Polymorphisms in the Angiogenesis Pathway and Non-small-Cell Lung Cancer Tumor Behavior: Implications in Risk Assessment and Clinical Outcome / Ramon Andrade de Mello [and others]
Pharmacology and Therapy of Angiogenesis. Angiogenic and Arteriogenic Factors: Their Role in the Treatment of Cancer and Arterial Regeneration / Wolfgang Schaper -- Physiological Roles and Therapeutic Implications of Hepatocyte Growth Factor for Angiogenesis / Hiroyuki Ohnishi [and others] -- Harnessing Endothelial Progenitor Cells for Therapeutic Angiogenesis / Alan W. Stitt, Reinhold J. Medina -- Microarray, MicroRNA, and Angiogenesis / Zufeng Ding, Xianwei Wang, Jawahar L. Mehta -- MicroRNA and Cardiovascular Disorders with a Focus on Angiogenesis / Elena Cavarretta, Giacomo Frati, Gianluigi Condorelli -- Overview of Angiogenesis Inhibitors from Natural Sources / Dipti Gatne, Veeranjaneyulu Addepalli
Summary Angiogenesis plays a key role in human physiology and pathophysiology. While necessary for tissue growth and development, uncontrolled angiogenesis plays a role in the progression of certain tumors as well as atherosclerosis. Lack of angiogenesis may be the basis of myocardial ischemia and stroke. Knowledge on the mechanisms of angiogenesis is growing very rapidly, and may lead to important drugs for therapy of a variety of clinical disorders. Experts from around the world have contributed a vast array of data on different aspects of angiogenesis in this volume edited by Professors Mehta and Dhalla. This information will be of immense help to basic scientists, clinicians and those involved in drug development
Notes Includes index
Bibliography Includes bibliographical references and index
Notes Print version record
Subject Neovascularization.
Neovascularization -- Therapeutic use.
Angiogenesis Inducing Agents.
Neovascularization, Pathologic.
Form Electronic book
Author Mehta, Jawahar.
Dhalla, Naranjan S.
LC no. 2012956286
ISBN 9781461458579 (electronic bk.)
1461458579 (electronic bk.)