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E-book
Author Clapp, Neal K., author

Title A Primate Model for the Study of Colitis and Colonic Carcinoma The Cotton-Top Tamarin (Saguinus oedipus)
Edition First edition
Published Boca Raton, FL : CRC Press, 2017

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Description 1 online resource (352 pages)
Summary "A Primate Model for the Study of Colitis and Colonic Carcinoma describes recent observations of the prevalence, pathogenesis, natural history, and time-course of idiopathic colitis and colonic carcinoma in the Cotton-Top Tamarin (CTT) model. Results of colonoscopy and mucosal biopsy are shown to evaluate the therapeutic efficacy of new anti-colitic agents. The contributions of antigenic profiles as a function of disease state, occurrence of extra-intestinal manifestations, and possible causal agents of colitis are also discussed. Prevalence of spontaneous CTT colonic carcinoma is considered from genetic influence, from promotion by colitis, and through the use of diagnostic and prognostic tools such as flow cytometry. Changes in fecal steroids, serum markers, colonic glycoprotein, polyamine metabolism, and immunobiology of CTTs are discussed in regard to disease condition. The book is an essential reference on the CTT model for gastroenterologists, oncologists, and all researchers interested in digestive diseases."--Provided by publisher
Subject Colitis -- Animal models
Colon (Anatomy) -- Cancer -- Animal models
Cottontop tamarin -- Diseases
Colitis -- Animal models
Colon (Anatomy) -- Cancer -- Animal models
Form Electronic book
ISBN 9781351069410
1351069411
9781351077866
1351077864