Description |
1 online resource (xxv, 431 pages) : illustrations |
Contents |
General principles of animal selection and normal physiological values -- Preanesthesia, anesthesia, chemical restraint, and the recognition and treatment of pain and distress -- Normal cardiac function parameters -- Measuring cardiac function -- Measuring vascular function and ventricular/arterial coupling dynamics -- Isolated heart preparations, problems, and pitfalls -- Cardiovascular effects of anesthetics, sedatives, postoperative analgesic agents, and other pharmaceuticals -- Naturally occurring and iatrogenic animal models of valvular, infectious, and arrhythmic cardiovascular disease -- Iatrogenic models of ischemic heart disease -- Iatrogenic, transgenic, and naturally occurring models of cardiomyopathy and heart failure -- Iatrogenic, congenic, and transgenic models of hypertension -- Naturally occurring, iatrogenic and transgenic models of atherosclerotic disease -- Animal models for the study of neurohumeral and central neural control of the cardiovascular system -- Other transgenic animal models used in cardiovascular studies |
Summary |
This new edition of "Animal Models in Cardiovascular Research" describes historical and recent advances in our understanding of the cardiovascular system from studies conducted in a variety of animal models. Since the last edition we have witnessed an explosion in the use of both congenic and transgenic animals. The use of specific knock-in and knock-out transgenic models has resulted in an avalanche of genetic, molecular and protein-based information that, potentially, could result in an amazing new array of treatment and management options. However, the results of these studies als |
Analysis |
dierfysiologie |
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animal physiology |
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modellen |
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models |
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cardiologie |
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cardiology |
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biomedische wetenschappen |
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biomedicine |
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Medicine (General) |
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Geneeskunde (algemeen) |
Bibliography |
Includes bibliographical references and index |
Notes |
Print version record |
Subject |
Cardiovascular system -- Diseases -- Animal models
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Cardiovascular system -- Research -- Methodology
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Cardiovascular system -- Diseases.
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Research.
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Diseases -- Animal models.
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Cardiovascular Diseases
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Research
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Cardiovascular System -- drug effects
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Disease Models, Animal
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research (function)
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MEDICAL -- Cardiology.
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Sciences de la vie.
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Biomédecine.
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Research
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Diseases -- Animal models
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Cardiovascular system -- Diseases
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Cardiovascular system -- Diseases -- Animal models
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Form |
Electronic book
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ISBN |
9780387959627 |
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0387959629 |
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