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Title From local invasion to metastatic cancer : involvement of distant sites through the lymphovascular system / edited by Stanley P.L. Leong
Published New York, NY : Humana Press, [2009]
©2009
Online access available from:
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Description 1 online resource (xxviii, 637 pages, 28 unnumbered pages of plates) : illustrations
Series Current clinical oncology
Current clinical oncology.
Contents Innovation and experience. Frontiers of cancer research: the metastasis challenge / Simone John, Christina H. Stuelten, and John E. Niederhuber -- Vascular endothelial growth factor: basic biology and clinical applications / Napoleone Ferrara -- Proliferation and cancer metastasis from the clinical point of view / Blake Cady -- Gastrointestinal cancer and the lymphatic system: patterns of micrometastasis and lymphatic mapping with clinicaloOutcome / Takashi Aikou [and others] -- Redefined lymphatic anatomy of the breast with clinical implications / Hiroo Suami, Wei-Ren Pan, and G. Ian Taylor -- Should axillary lymph node dissection be done for breast cancer? / Douglas Reintgen, Blake Cady, and Stanley P.L. Leong -- Tumor microenvironment and proliferation. Overview of tumor cells and the microenvironment / Richard E.B. Seftor [and others] -- Lymphangiogenesis and angiogenesis. Heme/lymphvasculogenesis, hem/lymphangiogenesis, hem/lymphangiotumorigenesis, and tumor hem/lymphangiogenesis: need for a terminology adjustment / Marlys H. Witte [and others] -- Tumor lymphangiogenesis: what we know and don't know / Antje Neeb and Jonathan P. Sleeman -- Diagnostic imaging of cancer. Molecular imaging of cancer: receptors, angiogenesis, and gene expression / Heiko Schöder -- MRI and ultrasound imaging of lymph nodes / Marika Decyk, Yuko Kono, and Robert Mattrey -- Molecular imaging of the sentinel lymph node via lymphoseek / Antonia Woehnl [and others] -- Lymphatic disorders in patients with cancer / Edwin C. Glass and Emily Iker -- 3D-CT lymphography for mapping metastatic breast sentinel node and axillary nodes / Koji Yamashita and Kazuo Shimizu -- Molecular imaging of neuroendocrine cancer by fusion SPET/CT / Jean L. Alberini [and others] -- Functional molecular imaging of prostate cancer lymph node metastases: adenovirus-mediated lymph node detection / Saul J. Priceman, Jeremy B. Burton, and Lily Wu -- Therapeutic targeting of the lymphovascular system. Therapeutic targeting of the lymphovascular system in cancer: promise and challenge / Bronislaw Pytowski and Jeffrey E. Gershenwald -- Comparison of liposomal and aqueous blue dye in visualization of Llymph nodes prior to lymphadenectomy / Peter Hirnle -- Molecular mechanisms of metastasis. The role of lymphangiogenesis in regional lymph node metastasis: animal models / S. David Nathanson, Cathie G. Miller, and James H. Paxton -- Sentinel lymph node chemokine microenvironment modulated by melanoma metastasis / Minoru Kitago [and others] -- Circulating and disseminated tumor cells from solid tumors -- research and clinical aspects / Catherine Alix-Panabières [and others] -- Head and neck cancer: an example for the role of chemokine receptors in tumor progression and metastasis / Anja Muller, Bernhard Homey, and Robert L. Ferris -- Tumor and lymph node Llymphangiogenesis / Michael Detmar -- Treg, chemokines, and other small molecules: role in metastasis and its prevention / Darryl A. Oble [and others]
Summary In human solid tumors, nodal status is the most important prognostic indicator for patients' outcome. Recent developments in the sentinel lymph node concept have resulted in a procedure to define the first draining node as the primary gateway through which the cancer will spread. In From Local Invasion to Metastatic Cancer: Involvement of Distant Sites through the Lymphovascular System, a panel of international authorities takes an in-depth look at the role of the lymphovascular system in the spread of cancer. The authors summarize the findings of the Second International Symposium on Cancer Metastasis: Basis for Rational Therapy summit. Specifically, the book presents important developments in the biology and clinical understanding of cancer metastasis, describes the relationship between tumor microenvironment and proliferation, and defines the process of lymphangiogenesis and angiogenesis with special reference to cancer metastasis. From Local Invasion to Metastatic Cancer: Involvement of Distant Sites through the Lymphovascular System provides molecular oncologists, radiologists, and clinicians the necessary information to study and develop new strategies to curb the process of metastasis
Analysis Cancer metastasis
Lymphovascular system
Bibliography Includes bibliographical references and index
Notes Print version record
Subject Metastasis.
Lymphatic Metastasis.
Antineoplastic Combined Chemotherapy Protocols -- therapeutic use.
Lymphangiogenesis -- drug effects.
Neoplasm Invasiveness.
Neovascularization, Pathologic -- physiopathology.
Genre/Form Congress.
Conference papers and proceedings.
Form Electronic book
Author Leong, Stanley P. L.
ISBN 1603270876 (e-isbn)
9781603270878 (e-isbn)