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Book Cover
Author Colman, Michael A., author

Title Mechanisms of atrial arrhythmias : insights from the development of a biophysically detailed model of the human atria / Michael A. Colman
Published Cham : Springer, 2014
Online access available from:
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Description 1 online resource (288 pages) : illustrations
Series Springer Theses
Springer theses.
Contents Background -- Development of a new model for simulating the electrical action potentials of human atrial myocytes -- Development of a family of regional cell models -- Autonomic regulation and pathophysiological remodelling -- 3D Anatomical Modelling of the Atria -- Pacemaking and autonomic regulation in the 3D sinoatrial node and atria -- Atrial Fibrillation -- Discussion
Summary This thesis describes the development of biophysically detailed computer models of the human atria and torso to study the underlying mechanisms of cardiac diseases, some of the most common causes of morbidity and mortality. This is a cross-disciplinary project, involving fundamentals of cardiac electrophysiology, physics of excitable media, applied mathematics and high performance scientific computing and visualisation. The author uses computer models to provide insights into the underlying mechanisms of the genesis of atrial fibrillation anddevelops novel techniques for the monitoring of atrial tachycardia
Notes Ph. D. University of Manchester (2013?)
Print version record
Subject Atrial arrhythmias.
Heart -- Computer simulation.
Genre/Form Academic theses.
Form Electronic book
ISBN 9783319016436 (electronic bk.)
3319016431 (electronic bk.)