| Description |
1 online resource (380 pages) |
| Contents |
Front Cover; Endocrinology of the Heart in Health and Disease; Copyright Page; Contents; List of Contributors; Foreword; Preface; Acknowledgments; I. The Heart as an Endocrine Organ; 1 Cardiac Natriuretic Peptides; Historical Perspective; Gene Structure of Natriuretic Peptides; Atrial Natriuretic Peptide; Brain or B-type Natriuretic Peptide; C-type Natriuretic Peptide; Translation, Processing, and Storage of Cardiac Natriuretic Peptides; Atrial Natriuretic Peptide; Brain or B-Type Natriuretic Peptide; C-Type Natriuretic Peptide |
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Circulating Concentrations, Forms, and Metabolism of Natriuretic PeptidesCirculating Levels; Circulating Forms and Metabolism; Natriuretic Peptide Receptors; Circulating Natriuretic Peptide Signal Peptides; Assays Measuring Natriuretic Peptides in the Circulation; Bioactivity; Hemodynamic; Renal; Endocrine; Integrative Role in Physiology and Pathophysiology; Natriuretic Peptide as Therapeutic Agents; Enhancing Bioactivity; NEP-I; Combined ACE and NEP Inhibitors; Combined ARB and NEP Inhibitors-New Frontier in Heart Failure Therapy; Natriuretic Peptides as Biomarkers in Heart Failure |
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Natriuretic Peptides in Diagnosis of Acute Decompensated Heart FailureBNP and NT-proBNP for Community Screening for Cardiac Impairment; B-Type Natriuretic Peptides for Prognosis in Heart Failure; Marker Guided Therapy in Heart Failure; References; 2 Adrenomedullin; Introduction; Molecular Forms, Structure, and Structure-Activity Relationships of Adrenomedullin; The Adrenomedullin Receptor; Cardiac Actions of Adrenomedullin; Effect of Adrenomedullin on Cardiac Contractility; Effect of Adrenomedullin on Cardiac Structure; Pathophysiological Function of Adrenomedullin in Cardiac Disease |
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Cardiac Hypertrophy and Heart FailureAcute Myocardial Infarction; Ischemia/Reperfusion; Clinical Applications of Adrenomedullin to Cardiac Disease; Effect of Adrenomedullin Administration in Patients with Heart Failure; Clinical Application of Adrenomedullin in Acute Myocardial Infarction; Clinical Trials with Adrenomedullin; Conclusion; References; 3 Endothelin-1 as a Cardiac-Derived Autocrine, Paracrine and Intracrine Factor in Heart Health and Disease; Introduction; Cardiac Production of ET-1; Cardiac ET-1 Production in Heart Disease; Expression of Cardiac ET Receptors |
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Intracellular ET Receptors: Evidence for an Intracrine Role of ET-1 in€the Cardiac CellCardiac Effects of ET-1; Mechanisms Underlying Inotropic Responses; Physiological and Pathophysiological Roles of Cardiac-Derived ET-1: General Concepts; ET-1 and the Aging Heart; Association of ET-1 With Cardiac Diseases; ET-1 in Cardiac Hypertrophy and Heart Failure; Endogenous Modulation of ET-1: Keeping ET-1 in Check?; Potential Beneficial Effects of ET-1 in Cardiac Function; Development of Clinical Strategies aimed at Targeting ET-1 |
| Bibliography |
Includes bibliographical references and index |
| Notes |
Online resource; title from digital title page (viewed on December 15, 2016) |
| Subject |
Heart -- Metabolism -- Endocrine aspects.
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Endocrinology.
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Myocardium -- metabolism
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Atrial Natriuretic Factor -- metabolism
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Endocrinology
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MEDICAL -- Physiology.
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SCIENCE -- Life Sciences -- Human Anatomy & Physiology.
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Endocrinology
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Heart -- Metabolism -- Endocrine aspects
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| Form |
Electronic book
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| Author |
Schisler, Jonathan C., editor
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Lang, Charles H., editor
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Willis, Monte S., editor
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| ISBN |
9780128031124 |
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0128031123 |
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