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Book Cover

Title Control of biofilm infections by signal manipulation / Naomi Balaban, editor ; foreword by J. William Costerton
Published Berlin : Springer, [2008]
Online access available from:
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Description 1 online resource (xvi, 175 pages) : illustrations (some color)
Series Springer series on biofilms ; v. 2
Springer series on biofilms ; v. 2
Contents Front Matter; Introduction; Bacterial Cell-to-cell Communication (Quorum Sensing); Detection In Vitro of Quorum-Sensing Molecules and Their Inhibitors; Quorum-Sensing Inhibitory Compounds; Mathematical Modeling of Quorum-Sensing Control in Biofilms; Animal Models Commonly Used to Study Quorum-Sensing Inhibitors; In Vivo Studies: Inhibiting Biofilm-Associated Bacterial Infections Using QSIs; Quorum Sensing in Streptococci; Ironing Out the Biofilm Problem:The Role of Iron in Biofilm Formation; Clinical Wound Healing Using Signal Inhibitors; Back Matter
Summary "The medical miracle of antibiotics is being eroded by the emergence and spread of bacterial drug resistance. This is compounded by the fact that bacterial bio-films are believed to be a common cause of persistent infections, where growing in a biofilm, bacteria are protected from the host's immune response and antibiotics. This book describes the molecular mechanisms of bacterial cell-to-cell communication (quorum sensing), the development of anti-biofilm inhibitors, and the use of such inhibitors to prevent and treat biofilm-associated bacterial infections in animals and humans."--Jacket
Bibliography Includes bibliographical references and index
Notes Print version record
Subject Bacterial diseases -- Treatment.
Cellular signal transduction.
Chemical inhibitors.
Bacterial Infections.
Quorum Sensing.
Signal Transduction.
Form Electronic book
Author Balaban, Naomi.
LC no. 2007941546
ISBN 3540738525 (hbk. ; alk. paper)
9783540738527 (hbk. ; alk. paper)