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Title Metal-on-metal bearings : a clinical practicum / Lynne C. Jones, Warren O. Haggard, A. Seth Greenwald, editors
Published New York, NY : Springer, 2014
Online access available from:
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Description 1 online resource (x, 200 pages) : illustrations (some color)
Contents Part I. Introduction -- Overview of Metal-on-Metal Implants / Lynne C. Jones, Warren O. Haggard and A. Seth Greenwald -- Bearing Surfaces for Joint Replacement: New Materials or New Problems / Stuart Goodman -- Part II. Clinical -- Outcome Studies for Metal-on-Metal Bearings: What Evidence-Based Medicine Tells Us / Michael A. Mont and Robert Pivec -- Metal Reactivity: Its Influence on Primary and Revision Outcomes / George Grammatopoulos, Hemant Pandit, Adrian Low and David Murray -- Are Metal Ion Levels a Trigger for Surgical Intervention? / David Langton -- Metal Sensitivity: Is It Possible to Determine Clinically? / Nadim J. Hallab and Paul H. Wooley -- Part III. Biology -- Wound Healing, Chronic Inflammation, and Immune Responses / Paul H. Wooley and Nadim J. Hallab -- Benign Responses to Orthopaedic Implants: Really? / H. John Cooper and Joshua J. Jacobs -- What Does the Histology Tell Us? / Thomas W. Bauer -- Part IV. Biomechanics -- Why Metal-on-Metal: What Laboratory Tests Have Shown Us / Peter Thomas, Burkhard Summer, Marc Thomsen, Veit Krenn and Jan Philippe Kretzer -- What Do the Retrievals Really Tell Us? / Robin Pourzal, Robert M. Urban and Markus A. Wimmer
Summary This book addresses the background and significance of the factors potentially influencing the clinical and biological outcomes of metal-on-metal hip implants. Metal-on-metal bearings were introduced and evaluated as an alternative to other bearing couples, particularly metal-on-polyethylene, due to their enhanced wear resistance as determined in laboratory testing. Initially, reports of short-term clinical outcomes were favorable and an increasing number of metal-on-metal prostheses were implanted. Subsequently, isolated case findings describing adverse tissue responses around the articulation became the harbinger of an increasing number of reports describing pseudotumors and other significant lymphocytic-based responses associated with metal-on-metal prostheses. Questions have been raised as to whether this is an implant, design, or patient-specific response. The reasons why some patients have a negative biological response and pathology while others do not remain to be determined, but tens of thousands of patients in the US, the UK, and around the world are considered to be at risk. Leading researchers and clinicians describe the issues related to the nature of the biological and pathological responses and the protocols that should be followed to determine if an adverse response is occurring
Bibliography Includes bibliographical references and index
Notes Online resource; title from PDF title page (SpringerLink, viewed November 4, 2013)
Subject Artificial joints -- Bearings -- Materials.
Biomedical materials.
Form Electronic book
Author Jones, Lynne C., editor
Haggard, Warren O., editor
Greenwald, A. Seth, editor
ISBN 1461489989
1461489997 (electronic bk.)
9781461489993 (electronic bk.)