| Description |
1 online resource |
| Contents |
Ch. 1. A magician of virology from Australia. The shaping of a biologist. Virus as an organism. The evaluations by Nobel committees. The golden age of virology and the changing science -- ch. 2. A divided Nobel Prize and a new era in immunology. The early Nobel Prizes in immunology. From virology to immunology. It takes two to tango. The Nobel committee reviews the discovery of immunological tolerance. The Nobel events in 1960. The post-Prize engagements of Burnet and Medawar -- two exceptional statesmen of science -- ch. 3. More Nobel Prizes in immunology. The origin of lymphocytes engaged in immune responses. The lack of recognition of the discoveries of B and T cells by a Nobel Prize. The basic structure of an antibody. One cell -- one antibody. One antigen selects a swarm of antibodies. The richness of antibodies is created by a lottery system. Antibodies cannot penetrate into cells. The Nobel assembly and an influential secretary. An embarrassed newly appointed secretary. The delayed Nobel Prize. The cell-bound immunity has an unexpected restriction. Innate immunity finally recognized again. Signalling without direct cell contacts -- ch. 4. Immunity, infections and transplantations. Inherited and acquired immune defects. Personal experiences of major health challenges and engagement in research. The evolutionary interplay of viruses and their hosts. The development in tissue transplantations in humans. A committed female scientist. Complications of medically induced immune suppression. A management of bereavement. ch. 5. Transgressing borders in science and scenes of life. The assimilated Jew and the budding scientist. Rutherford's laboratory. The turmoil of the First World War. The first stay with Bohr -- the hafnium years. The deliberations by the Nobel committee on the discovery of hafnium. The age of the Earth and the rare earth elements. Years of interlude in Freiburg. Return to Copenhagen -- the indicator method comes of age. The evaluation of the indicator method by the Nobel committee. The shadow of the Second World War. A final home country. The Nobel Prize. Modern tracer techniques in biology, medicine and archaeology. Life after the Nobel Prize |
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Ch. 6. Making sense of hearing. The early years of studies. The inner ear is so beautiful that I must study it. The Swedish connection. A discovery that caught the ear of the Nobel committee. The decisive year of 1961. The Prize ceremony. A different kind of Nobel lecture. A meeting of minds. Our senses and Nobel Prizes. A final home in Hawaii; East meets West. A gracious will -- ch. 7. Unraveling the complexity of protein folding. The great sage. The birth of a new branch of science. The lady of crystals. A scientist obsessed by hemoglobin. Enter Kendrew. The genius of chemistry. Critical turning points in the understanding of the structure of hemoglobin. Understanding the structure of myoglobin. The delayed Nobel Prize to Hodgkin. Protein crystallography comes of age. Towards the finish line. Life after the Nobel Prize -- ch. 8. "It's so beautiful, you see, so beautiful!". The great DNA discovery. The role of nucleic acids finally appreciated. Bragg makes strategic nominations. The review by a crystallographer. Pauling reflects on nominations for the discovery of the structure of DNA. The temperature rises and a powerful nomination. Tiselius' final analysis. The Karolinska Institute -- a slow starter that won the trophy. Honest Jim and the double helix. The short life of a devoted scientist. Classification of viruses. Wilkins or Franklin? Crick and Klug discuss Franklin's qualifications as a scientist. Three or two? Days of festivities in December 1962. The tallest beacon among molecular biologists. Living for 60 years with the golden helix. The third man remained the third man. Franklin's posthumous recognition. What is a gene? -- ch. 9. Coda. Paradigmatic discoveries. Genius is a fire that lights itself. The importance of lifestyle. The driving force in the pursuit of science. Internalism and externalism. Science and politics. Seeds and deeds |
| Summary |
Each year the Nobel Prizes in the natural sciences reveal amazing discoveries. New milestones in the relentless advance of science are identified. The growth of knowledge and its evolution can be researched in the Nobel archives where nominations are kept secret for 50 years after the awards have been made. They represent a treasure for real-time assessment of science. Norrby's earlier book, Nobel Prizes and Life Sciences (2010) examined the unique archival records until 1959. The present book takes us up to 1962, surveying a range of dazzling discoveries. All prizes in immunology are reviewed. Their impact on our capacity to control infectious diseases and transplant organs are highlighted. The Nobel year 1962 is exceptional in recognizing the most major advance in biology since Darwin in 1859 presented his theory of evolution. This was the dramatic discovery of the double-helix structure of DNA by Watson and Crick in 1953. The era of molecular biology had begun. Its explosive development continues into the present |
| Notes |
Print version record |
| Subject |
Allergy -- History
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Immunology -- History
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Nobel Prizes.
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Biology -- History
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Biology -- Research -- History
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Medicine -- Research -- History
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Nobel Prize
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Allergy
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Biology
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Biology -- Research
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Immunology
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Medicine -- Research
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Nobel Prizes
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| Genre/Form |
History
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| Form |
Electronic book
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| ISBN |
1306183219 |
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9781306183215 |
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9789814522007 |
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9814522007 |
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