| Description |
1 online resource (378 pages) |
| Contents |
Cover; Title Page; Copyright; Contents; Contributors; Preface; Chapter 1 History of blood transfusion and patient blood management; Introduction; Blood: early beliefs and practice; Blood transfusion; Transfusion with animal blood; First human blood transfusion; Karl Landsteiner to the twenty-first century; New transfusion issues emerge; The new paradigm; References; Chapter 2 The ethical complexities of transfusion-free medicine, surgery and research; Introduction; Ethics and informed consent; Children, assent, and consent; Professionalism and transfusion-free practices; Jehovah's witnesses |
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Organ transplantationResearch ethics; References; Chapter 3 Transfusion therapy-Balancing the risks and benefits; Introduction/overview; The clinical utility of transfusion therapy; Red blood cell transfusion; Platelet transfusions; Plasma component therapy; Cryoprecipitate; Transfusion-related adverse reactions; Hemolytic transfusion reactions; TRALI; Sepsis; Summary and conclusions; References; Chapter 4 The physiology of anemia and the threshold for blood transfusion; Introduction; Etiologies of anemia; Physiologic response to anemia; The transfusion threshold; Risks of blood transfusion |
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Infectious complicationsTRALI; TACO; Hemolytic reactions; Febrile reactions; Metabolic effects; Immunological effects; Summary; References; Chapter 5 Blood transfusion in surgery; Introduction; The cost-effectiveness of blood products: a surgical perspective; Pre-operative optimization of the surgical patient; Intra-operative approach to blood conservation; A. Surgical judgment; B. Surgical technique; C. Intra-operative cell salvage (ICS); D. Acute normovolemic hemodilution (ANH); E. Anesthesia management; F. Coagulation management; Post-operative care; Trends in transfusion-free surgery |
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ConclusionReferences; Chapter 6 Current view of coagulation system; Normal hemostasis; Vascular phase; Platelet phase; Coagulation phase; Fibrin formation; Fibrinolysis; Regulation of hemostasis; Abnormal hemostasis; Congenital hemostatic disorders; Acquired hemostatic disorders; Evaluation of hemostasis; History and physical examination; Coagulation tests; Preoperative screening tests; Thromboelastography; Rotational thromboelastometry (ROTEM®); Management of intraoperative coagulation; Clinical coagulation; Coagulation management; Hemostatic drug therapy |
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Prolysins (tPA, urokinase, and streptokinase)Antifibrinolytics; Procoagulants; Anticoagulants; References; Chapter 7 Topical hemostatic agents; Introduction; History of hemostatics; The biology of hemostasis; Hemostasis in surgery; Safety of hemostatics; Topical hemostatics; Passive agents; Adhesive hemostatics (fibrin glues); Surgical settings; Topical hemostatics (Passive agents); Collagen-based products; Cellulose-based products; Gelatin agents; References; Chapter 8 Intraoperative strategies for transfusion-free medicine; Introduction; General considerations; Autologous blood |
| Summary |
This book aims to be a guide to the practice of blood conservation. The first chapter discusses the legal and administrative aspects of bloodless medicine describing the legal principles and practical issues relatd to refusal of transfusion. The second is on balancing the risks and benefits of transfusion includes clinical vignettes of appropriate and inappropriate transfusion. The remainder of the book covers the principles and practice of bloodless medicine, including a chapter on the scientific issues of haemostasis and the investigation of bleeding idsorders. The book concludes with cha |
| Notes |
Acute normovolemic (isovolemic) hemodilution |
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Print version record |
| Subject |
Blood -- Collection and preservation.
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Blood -- Transfusion -- Complications.
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Blood -- Transfusion -- Law and legislation.
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Bloodless Medical and Surgical Procedures
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Blood Preservation
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Blood -- Collection and preservation
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Blood -- Transfusion -- Complications
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Blood -- Transfusion -- Law and legislation
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| Form |
Electronic book
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| ISBN |
9781118554692 |
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1118554698 |
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