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Title Vascular-targeted therapies in oncology / editor, Dietmar W. Siemann
Published Chichester, West Sussex, England ; Hoboken, NJ : John Wiley & Sons, [2006]
Online access available from:
Wiley Online Books    View Resource Record  


Description 1 online resource (xvii, 350 pages, 8 unnumbered pages of plates) : illustrations (some color)
Contents Tumor vasculature : a target for anticancer therapies / Dietmar W. Siemann -- Abnormal microvasculature and defective microcirculatory function in solid tumors / Peter Vaupel -- The role of microvasculature in metastasis formation / Oliver Stöltzing, Lee M. Ellis -- Development of agents that selectively disrupt tumor vasculature : a historical perspective / David J. Chaplin, Sally A. Hill -- Morphologic manifestations of vascular-disrupting agents in preclinical models / Mumtaz V. Rojiani, Amyn Rojiani -- Molecular recognition of the colchicine binding site as a design paradigm for the discovery and development of vascular disrupting agents / Kevin G. Pinney -- Combined modality approaches using vascular-disrupting agents / Wenyin Shi, Michael R. Horsman, Dietmar W. Siemann -- Vascular-targeting therapies and hyperthermia / Michael R. Horsman, Rumi Murata -- Flavones and xanthenones as vascular-disrupting agents / Bronwyn G. Siim, Bruce C. Baguley -- Targeting inside-out phospholipids on tumor blood vessels in pancreatic cancer / Adam W. Beck, Rolf Brekken, Philip E. Thorpe -- Cadherin antagonists as vascular-targeting agents / Orest Blaschuk, Tracey M. Rowlands -- Alphastatin : a pluripotent inhibitor of activated endothelial cells / Carolyn A. Staton, Claire Lewis -- Cationic lipid complexes to target tumor endothelium / Uwe Michaelis, Michael Teifel -- Development of vascular-targeting cancer gene therapy / Graeme J. Dougherty, Peter D. Davis, Shona T. Dougherty -- Vascular-disrupting strategies combined with bacterial spores targeting hypoxic regions of solid tumors / G-One Ahn, J. Martin Brown -- Imaging the effects of vascular-targeting agents / Susan M. Galbraith -- Clinical progress in tumor vasculature-disrupting therapies / Andrew M. Gaya, Gordon J.S. Rustin -- Use of vascular-disrupting agents in non-oncology indications / Joseph C. Randall, Scott Young
Bibliography Includes bibliographical references and index
Notes Master and use copy. Digital master created according to Benchmark for Faithful Digital Reproductions of Monographs and Serials, Version 1. Digital Library Federation, December 2002. MiAaHDL
Print version record
Subject Neoplasms -- drug therapy.
Angiogenesis Inhibitors -- therapeutic use.
Blood Vessels -- drug effects.
Drug Delivery Systems.
Endothelial Cells -- drug effects.
Neovascularization, Pathologic.
Blood-vessels -- Effect of drugs on.
Cancer -- Chemotherapy.
Neovascularization inhibitors.
Genetic Therapy -- methods.
Form Electronic book
Author Siemann, Dietmar W.
ISBN (alk. paper)
(alk. paper)