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Title Myeloproliferative neoplasms : biology and therapy / edited by Srdan Verstovsek, Ayalew Tefferi
Published New York : Humana Press, ©2011

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Description 1 online resource (x, 228 pages) : illustrations (some color)
Series Contemporary hematology
Contemporary hematology.
Contents Diagnosis and classification of the BCR-ABL1-negative myeloproliferative neoplasms -- Genetics of the myeloproliferative neoplasms -- Cytogenetic findings in classical MPNs -- Prognostic factors in classic myeloproliferative neoplasms -- Therapy of polycythemia vera and essential thrombocythemia -- Conventional and investigational therapy for primary myelofibrosis -- Hematopoietic cell transplantation for myelofibrosis -- JAK2 inhibitors for therapy of myeloproliferative neoplasms -- Blastic transformation of classic myeloproliferative neoplasms -- Eosinophilic disorders: differential diagnosis and management -- Pathogenesis, diagnosis, classification, and management of systemic mastocytosis
Summary This succinct resource provides an ideal balance of the biology and practical therapeutic strategies for classic and non-classic BCR-ABL-negative myeloproliferative neoplasms. Utilizing current World Health Organization nomenclature, classification, and diagnostic criteria, international experts have assembled to convey the most up-to-date knowledge in this rapidly evolving field. The opening chapters cover the diagnosis and classification, genetics, cytogenetic findings, and prognostic factors of MPNs. Further chapters explore therapies specific to the different disease entities, including polycythemia vera, essential thrombocytopenia, myelofibrosis, and eosinophilic disorders, and mastocytosis. Unique areas of discussion include JAK2 inhibitor therapy, hematopoietic stem cell transplantation, and blastic transformation. A valuable reference for practicing hematologists, this forefront book enriches our understanding of recent discoveries and their impact on conventional and investigational treatments
Bibliography Includes bibliographical references and index
Notes English
Print version record
In Springer eBooks
Subject Bone marrow -- Tumors.
Myeloproliferative disorders.
Biochemistry.
Myelodysplastic-Myeloproliferative Diseases
Myelodysplastic-Myeloproliferative Diseases -- therapy
Bone Marrow Neoplasms -- therapy
Bone Marrow Neoplasms
Myeloproliferative Disorders
Biochemistry
biochemistry.
MEDICAL -- Oncology.
HEALTH & FITNESS -- Diseases -- Cancer.
Médecine.
Bone marrow -- Tumors
Myeloproliferative disorders
Form Electronic book
Author Verstovsek, Srdan.
Tefferi, Ayalew.
LC no. 2010937641
ISBN 9781607612667
1607612666
1282972146
9781282972148
9786612972140
6612972149