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Title Osteoimmunology : interactions of the immune and skeletal systems II / Yongwon Choi, eidtor
Published New York : Springer, [2010]
©2010
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Description 1 online resource (xii, 127 pages) : illustrations
Series Advances in experimental medicine and biology, 0065-2598 ; v. 658
Advances in experimental medicine and biology ; v. 658
Contents The role of bone marrow edema and lymphangiogenesis in inflammatory-erosive arthritis / Edward M. Schwarz [and others] -- Activation of [gamma][delta] T cells by bisphosphonates / Keith Thompson [and others] -- Identification of cell cycle-arrested quiescent osteoclast precursors in vivo / Naoyuki Takahashi [and others] -- Megakaryocyte-bone cell interactions / Melissa A. Kacena and Wendy A. Ciovacco -- Regulation of osteoblast differentiation by Runx2 / Toshihisa Komori -- Communication between ephrinB2 and ephB4 within the osteoblast lineage / T.J. Martin [and others] -- The unexpected link between osteoclasts and the immune system / Hiroshi Takayanagi -- NFATc1 in inflammatory and musculoskeletal conditions / Antonios O. Aliprantis and Laurie H. Glimcher -- Novel functions of RANK(L) signaling in the immune system / Andreas Leibbrandt and Josef M. Penninger -- Eph and ephrin interactions in bone / Koichi Matsuo -- How do bone cells secrete proteins? / Haibo Zhao [and others] -- Regulation of osteoclast apoptosis by Bcl-2 family protein Bim and caspase-3 / Sakae Tanaka [and others] -- Regulation of bone formation and immune cell development by Schnurri proteins / Dallas C. Jones and Laurie H. Glimcher
Summary It has only recently been appreciated that the immune and skeletal systems have major interactions. It is now well documented that osteoclasts, which are important cellular mediators of skeletal homeostasis, are derived from hematopoietic precursors that also give rise to immune cells. In addition, numerous cytokines that were first shown to regulate immune cell function have also been demonstrated to regulate bone cells and influence skeletal health. Conversely, products of bone cells appear critical for the engraftment of marrow in bone, the normal development of the hematopoietic and immune systems and provide niche for long-term memory B and T cells. In the past scientists involved in immune and bone cell investigations have rarely interacted in a significant way as these disciplines have developed independently and, for the most part, remain separate. The conference will bring together leading international scientists from both fields to interact so that new collaboration can develop and more rapid progress in understanding the relationships between these fields can be achieved. Short talks will be selected from abstracts from the international community. This conference will have a format to provide an environment of maximum interaction and interchange through lectures, posters, and open discussion
Bibliography Includes bibliographical references and index
Notes Print version record
Subject Immunology.
Musculoskeletal system.
Bone and Bones -- immunology.
Bone Diseases -- immunology.
Bone Marrow Diseases -- immunology.
Osteoblasts -- immunology.
Osteoclasts -- immunology.
Genre/Form Congress.
Conference papers and proceedings.
Form Electronic book
Author Choi, Yongwon.
Aegean Conferences.
International Conference on Osteoimmunology : Interactions of the Immune and Skeletal Systems (2nd : 2008 : Rhodes, Greece)
LC no. 2009937138
ISBN 9781441910509
1441910506
9781441910493
1441910492
Other Titles Interactions of the immune and skeletal systems II