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Title Myeloproliferative neoplasms : biology and therapy / edited by Srdan Verstovsek, Ayalew Tefferi
Published New York : Humana Press, [2011]
©2011
Online access available from:
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Description 1 online resource (x, 228 pages) : illustrations (some color)
Series Contemporary hematology
Contemporary hematology.
Contents Diagnosis and classification of the BCR-ABL1-negative myeloproliferative neoplasms -- Genetics of the myeloproliferative neoplasms -- Cytogenetic findings in classical MPNs -- Prognostic factors in classic myeloproliferative neoplasms -- Therapy of polycythemia vera and essential thrombocythemia -- Conventional and investigational therapy for primary myelofibrosis -- Hematopoietic cell transplantation for myelofibrosis -- JAK2 inhibitors for therapy of myeloproliferative neoplasms -- Blastic transformation of classic myeloproliferative neoplasms -- Eosinophilic disorders: differential diagnosis and management -- Pathogenesis, diagnosis, classification, and management of systemic mastocytosis
Summary This succinct resource provides an ideal balance of the biology and practical therapeutic strategies for classic and non-classic BCR-ABL-negative myeloproliferative neoplasms. Utilizing current World Health Organization nomenclature, classification, and diagnostic criteria, international experts have assembled to convey the most up-to-date knowledge in this rapidly evolving field. The opening chapters cover the diagnosis and classification, genetics, cytogenetic findings, and prognostic factors of MPNs. Further chapters explore therapies specific to the different disease entities, including polycythemia vera, essential thrombocytopenia, myelofibrosis, and eosinophilic disorders, and mastocytosis. Unique areas of discussion include JAK2 inhibitor therapy, hematopoietic stem cell transplantation, and blastic transformation. A valuable reference for practicing hematologists, this forefront book enriches our understanding of recent discoveries and their impact on conventional and investigational treatments
Bibliography Includes bibliographical references and index
Notes Print version record
Subject Bone marrow -- Tumors.
Myeloproliferative disorders.
Bone Marrow Neoplasms -- therapy.
Myelodysplastic-Myeloproliferative Diseases -- therapy.
Myelodysplastic-Myeloproliferative Diseases.
Form Electronic book
Author Verstovsek, Srdan.
Tefferi, Ayalew.
ISBN 9781607612667 (electronic bk.)
1607612666 (electronic bk.)