| Description |
1 online resource (xvi, 368 pages) : illustrations |
| Contents |
Introduction / Dimitri Novitzky and David K.C. Cooper -- Historical aspects of the diagnosis of death / Félix Bacigalupo and Daniela A. Huerta Fernández -- The determination of brain death / Curtis M. Keller, Boris Chulpayev, and Michael Hoffmann -- Legal aspects of brain death and organ donorship / Ricky T. Munoz and Mark D. Fox -- Ethical issues in organ donation from brain-dead donors / Mark D. Fox and Ricky T. Munoz -- Pathophysiology of brain death in small animal models / Bernhard Floerchinger, Nicholas L. Tilney, and Stefan G. Tullius -- Pathophysiology of brain death and effects of hormonal therapy in large animal models / Dimitri Novitzky, Winston N. Wicomb, and David K.C. Cooper -- The efficacy of thyroid hormone therapy in brain-dead heart donors: A review of thyroid function in health and disease / Lawrence E. Shapiro and Tatiana Baron -- The inflammatory response to brain death / Anne Barklin, Christine Lodberg Hvas, and Else Toennesen -- The influence of brain death and intensive care management on donor organs: Assessment of inflammatory markers / Wayel Jassem and Susan V. Fuggle -- Brain death-induced inflammation: Possible role of the cholinergic anti-inflammatory pathway / Simone Hoeger and Benito A. Yard -- Innate immunity and injury during brain death: Opportunities for intervention / Marc A. Seelen, Henri G.D. Leuvenink, and Rutger J. Ploeg -- Selection of the brain-dead potential organ donor / Kadiyala V. Ravindra, Keri E. Lunsford, and Paul C. Kuo -- Infectious disease aspects of the brain-dead potential organ donor / Nicole M. Theodoropoulos and Michael G. Ison -- Malignancy in the brain-dead organ donor / Michael A. Nalesnik, Ron Shapiro, and Michael G. Ison -- Early clinical experience of hormonal therapy in the brain-dead potential organ donor / Dimitri Novitzky, Burcin Ekser, and David K.C. Cooper -- Assessment, monitoring, and management of brain-dead potential organ donors in the USA / Demetrios Demetriades and Lydia Lam -- Assessment, monitoring, and management of brain-dead potential organ donors in Europe / Gabriel J. Echeverri and Bruno G. Gridelli -- Assessment, monitoring, and management of brain-dead potential organ donors in Australia / Peter S. Macdonald [and others] -- Management of the brain-dead organ donor: Persectives of the transplant coordinator / Nicole T. Farina and David K.C. Cooper -- Surgical aspects of throacic and abdominal organ procurement from brain-dead donors / Michael J. Anstadt, Paul C. Kuo, and Kadiyala V. Ravindra -- Impact of brain death on storage of the heart / Winston N. Wicomb and David K.C. Cooper -- Impact of brain death on abdominal organs and allograft preservation strategies / Coney Bae [and others] -- Functional repair of brain death-induced injury / Henri G.D. Leuvenink, Marc A.J. Seelen, and Rutger J. Ploeg -- Functional repair of brain death-injured donor lungs / Jonathan C. Yeung, Marcelo Cypel, and Shaf Keshavjee -- Thyroid hormone therapy to the recipient of a heart from a brain-dead donor / Dimitri Novitzky and David K.C. Cooper -- Current and potential future trends in the management of the brain-dead organ donor / Octavio E. Pajaro and James K. Kirklin -- Maximizing utilization of the potential decreased donor: The challenge continues / Eliezer Katz |
| Summary |
Addressing all aspects of brain death and thoroughly detailing how a potential organ donor should be maintained to ensure maximum use of the organs and cells, The Brain-Dead Organ Donor: Pathophysiology and Management is a landmark addition to the literature. This first-of-its-kind, multidisciplinary volume will be of interest to a large section of the medical community. The first section of the book reviews the historical, medical, legal, and ethical aspects of brain death. That is followed by two chapters on the pathophysiology of brain death as investigated in small and large animal models. This includes a review of the many hormonal changes, including the neuroendocrine- adrenergic 'storm', that takes place during and following the induction of brain death, and how they impact metabolism. The next section of the book reviews various effects of brain death, namely its impact on thyroid function, the inflammatory response that develops, and those relating to innate immunity. The chapters relating to assessment and management of potential organ donors will be of interest to a very large group of transplant surgeons and physicians as well as critical care and neurocritical care physicians and nurses. Neurologists, endocrinologists, neurosurgeons, and pathologists will also be interested, especially in the more basic science sections on various aspects of brain-death and hormonal therapy. Organ procurement organizations and transplant coordinators worldwide will also be interested in this title. Other chapters will be of interest to medical historians, medico-legal experts, and ethicists |
| Bibliography |
Includes bibliographical references and index |
| Notes |
English |
| In |
Springer eBooks |
| Subject |
Donation of organs, tissues, etc.
|
|
Brain death.
|
|
Transplantation of organs, tissues, etc.
|
|
Organ donors.
|
|
Surgery.
|
|
Pathology.
|
|
Tissue Donors
|
|
Brain Death -- physiopathology
|
|
Organ Preservation -- methods
|
|
Tissue and Organ Harvesting
|
|
Tissue and Organ Procurement
|
|
Brain Death
|
|
Tissue Transplantation
|
|
Organ Transplantation
|
|
Transplantation
|
|
General Surgery
|
|
Pathology
|
|
surgery (health care function)
|
|
pathology.
|
|
MEDICAL -- Allied Health Services -- General.
|
|
Organ donors
|
|
Brain death
|
|
Donation of organs, tissues, etc.
|
|
Transplantation of organs, tissues, etc.
|
| Form |
Electronic book
|
| Author |
Novitzky, Dimitri.
|
|
Cooper, D. K. C. (David K. C.), 1939-
|
| ISBN |
1461443032 |
|
9781461443032 |
|
1461443040 |
|
9781461443049 |
|
1283740486 |
|
9781283740487 |
|
