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Title Cardiovascular calcification and bone mineralization / Elena Aikawa, Joshua D. Hutcheson, editors
Published Cham : Humana Press, 2020
Online access available from:
Springer eBooks    View Resource Record  


Description 1 online resource
Series Contemporary cardiology, 2196-8969
Contemporary cardiology (Totowa, N.J.)
Contents Part I. Cardiovascular Calcification -- Chapter 1. The History of Cardiovascular Calcification -- Chapter 2. Basic Pathology of Arterial and Valvular Calcification in Humans -- Chapter 3. Developmental Pathways and Aortic Valve Calcification -- Chapter 4. Differential Mechanisms of Arterial and Valvular Calcification -- Chapter 5. Calcifying Extracellular Vesicles: Biology, Characterization, and Mineral Formation -- Chapter 6. Role of Biomechanical Stress and Mechanosensitive miRNAs in Calcific Aortic Valve Disease -- Chapter 7. The Role of Chronic Kidney Disease in Ectopic Calcification -- Chapter 8. The Role of Calcification in Peripheral Artery Disease -- Chapter 9. Bioprosthetic Heart Valve Calcification: Clinicopathologic Correlations, Mechanisms, and Prevention -- Part II. Ectopic Calcification -- Chapter 10. Electron Microscopy for the Characterization of Soft Tissue Mineralization -- Chapter 11. Cardiovascular Calcification in Hutchinson-Gilford Progeria and Correlation with Age-Related Degenerative Calcification -- Chapter 12. Calcinosis in Scleroderma -- Chapter 13. Placental Calcification: Long-standing Questions and New Biomedical Research Directions -- Chapter 14. Heterotopic Ossification Following Traumatic Blast Injury -- Part III. Bone Mineralization -- Chapter 15. The Paradoxical Relationship Between Skeletal and Cardiovascular Mineralization -- Chapter 16. Cellular Contributors to Bone Homeostasis -- Chapter 17. Bone Biology, Modeling, Remodeling, and Mineralization -- Chapter 18. Osteoclasts in Cardiovascular Calcification -- Part IV. Imaging, Treatment, and Target Discovery -- Chapter 19. Imaging Cardiovascular Calcification Activity with 18F-Fluoride PET -- Chapter 20. The Role of Elastin Degradation in Vascular Calcification: Possibilities to Repair Elastin and Reverse Calcification -- Chapter 21. Clinical Trials and Calcification-Based Treatment Decisions -- Chapter 22. Surgical Versus Transcatheter Aortic Valve Replacement -- Chapter 23. Target Discovery in Calcification Through Omics and Systems Approaches
Summary The book covers the basic science and clinical aspects of cardiovascular calcification and bone mineralization. Cardiovascular calcification is the leading predictor of cardiovascular morbidity and mortality, with a predictive value more significant than blood lipid levels. The presence of calcific mineral in cardiovascular tissues alters biomechanical performance, increasing workload on the heart and potentiating atherosclerotic plaque rupture and subsequent heart attack and stroke. This book examines the role of calcification in cardiovascular disease covering topics such as calcification in the atherosclerotic plaques and aortic valves arteries and valves, aortic valve replacement, peripheral artery disease, imaging of early calcification and target discovery. In addition, various forms of ectopic calcification as well as mechanisms of bone mineralization are discussed. Cardiovascular Calcification and Bone Mineralization is an essential resource for clinicians, researchers, and other medical professionals in cardiology, pathology, and biomedical engineering
Notes Includes index
Subject Calcification, Physiologic.
Vascular Calcification.
Cardiovascular system -- Calcification
Minerals in the body.
Biomedical engineering.
Cardiovascular medicine.
Medical -- Allied Health Services -- Medical Technology.
Medical -- Cardiology.
Medical -- Pathology.
Minerals in the body
Form Electronic book
Author Aikawa, Elena.
Hutcheson, Joshua Daniel.
ISBN 3030467252