Description |
1 online resource (pages .) |
Series |
Endocrine development ; v. 16 |
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Endocrine development ; v. 16.
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Contents |
Cover; Contents; Foreword; Preface; Voyages of Discovery; Abstract; Vitamin D and Rickets; Parathyroid Hormone; Calcitonin; Parathyroid Hormone-Related Peptide; Fibroblast Growth Factor 23; References; Physiology of Calcium, Phosphate and Magnesium; Abstract; Calcium Physiology; Control of Plasma Calcium; Transmembrane Calcium Transport; Magnesium Metabolism; Phosphate Metabolism; The Calcium Cascade; The Calcium Sensing Receptor; The Parathyroid Glands; Parathyroid Hormone; The PTH Receptors; Intracellular Signalling; The Target Organs; Parathyroid Hormone-Related Peptide; Calcitonin |
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Alkaline PhosphataseVitamin D Metabolism; Conclusions; References; Physiology of Bone; Abstract; Skeletal Development; Osteoblast Differentiation and Function; Bone and Cartilage Matrix Collagens and Their Modifying Enzymes; Osteocytes and Bone Lining Cells; Osteoclasts; Hormones and Mineral Homeostasis; The Nervous System and Bone; Functional Adaptation of Bone to Load Bearing; Healthy Bones for Life: Nutrition and Exercise in Bone Physiology; Conclusions; References; Bone Biopsy: Indications and Methods; Abstract; Bone Biopsy Procedure; Sample Processing; Histomorphometric Parameters |
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Bone Metabolism in Children and AdolescentsIndications for Bone Biopsy in Paediatrics; Conclusions; Acknowledgements; References; Bone Densitometry: Current Status and Future Perspectives; Abstract; What Is Bone Mineral Density?; Assessment of Bone Density; Measurement Principles; Dual-Energy X-Ray Absorptiometry; Volumetric Bone Density for Age; Bone Mineral Content for Height; Allometric Approach; Regression Models; Mechanostat Functional Model; Diagnostic Potential of Dual-Energy X-Ray Absorptiometry; Quantitative Computed Tomography |
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Diagnostic Potential of Quantitative Computed TomographyMagnetic Resonance Imaging; Quantitative Ultrasound; Guidelines; References; A Practical Approach to Hypocalcaemia in Children; Abstract; Physiological Response to Hypocalcaemia; Signs and Symptoms of Hypocalcaemia; Investigations; Aetiology of Hypocalcaemia -- Classification; Hypocalcaemia with Low or Undetectable PTH; The 22q Deletion (Di George) Syndrome; Other Forms of Familial Hypoparathyroidism; Acquired Hypoparathyroidism; Hypomagnesaemia; Hypomagnesaemia with Hypomagnesuria; Hypomagnesaemia with Hypermagnesuria |
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Acquired HypomagnesaemiaHypocalcaemia with Normal Parathyroid Hormone; Antibodies to the Calcium-Sensing Receptor; Hypocalcaemia with a High Parathyroid Hormone; Disorder of Vitamin D Supply or Metabolism; Osteopetrosis; Treatment; Conclusions; References; A Practical Approach to Problems of Hypercalcaemia; Abstract; Steady State Calcium Homeostasis; Pathophysiology of Hypercalcaemia; Clinical Features and Clinical Evaluation of Hypercalcaemia; Investigation of Hypercalcaemia; Specific Conditions Leading to Hypercalcaemia during Childhood |
Summary |
Over recent decades, innovative diagnostic technologies, new therapeutic approaches and steady progress in medical genetics have helped establish the field of bone disease as a stand-alone specialty. Summarizing current knowledge, the physiology of calcium, magnesium and phosphate metabolism, the technique of bone biopsy and uses and pitfalls of bone density scanning are discussed. The main part of this publication describes in detail the disorders associated with hypocalcemia, hypercalcemia, rickets, phosphate metabolism, primary and secondary osteoporosis. The genetic nature of many of these conditions is highlighted and each condition is referred to by the number of its OMIM entry. The final chapter, which distinguishes this book from previous publications on the topic, comprises case reports illustrating some of the problems that are examined in previous chapters. This comprehensive account of disorders related to bone and mineral metabolism makes essential reading for pediatric endocrinologists as well as for clinicians who wish to gain a practical understanding of this important topic |
Bibliography |
Includes bibliographical references and indexes |
Notes |
Print version record |
Subject |
Bone diseases in children -- Case studies
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Calcium metabolism disorders in children -- Case studies
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Children.
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Human beings.
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Adolescent
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Child
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Humans
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Calcium Metabolism Disorders -- physiopathology
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Bone Diseases -- physiopathology
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children (people by age group)
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Homo sapiens (species)
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Children
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Bone diseases in children
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Calcium metabolism disorders in children
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Genre/Form |
Case studies
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Form |
Electronic book
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Author |
Allgrove, Jeremy
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Shaw, Nick
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S. Karger (Firm)
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LC no. |
2009018333 |
ISBN |
9783805591621 |
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3805591624 |
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1283153491 |
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9781283153492 |
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3805591616 |
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9783805591614 |
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