Contents: Lysosome as degradative organelle -- Transcriptional regulation of lysosomal and autophagic function -- Promoting clearance through overexpression of TFEB in lysosomal storage disorders -- TFEB regulation by phosphorylation -- Imaging approaches to identify phosphatase regulating TFEB nuclear translocation -- Role of the lysosomal calcium channel TRPML1 in TFEB nuclear translocation
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