Title Extracellular domain structures from calcium-sensing and GABA(B) receptors / Qing R. Fan

Published London : Henry Stewart Talks, 2019

Online access available from: HSTalks Biomedical & Life Sciences Collection    View Resource Record

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Description 1 online resource (1 streaming video file (36 min.) : color, sound) Series Structural and functional insights into GPCR signalling, 2056-452X Henry Stewart talks. Biomedical & life sciences collection. Structural and functional insights into GPCR signalling Contents Contents: Crystal structures of human GABA(B) receptor extracellular domain in multiple functional states -- Agonist vs. antagonist recognition -- Identification of novel heterodimer interface associated with receptor activation -- Crystal structures of human CaSR in the inactive and active conformations -- Discovery of L-amino acids as orthosteric agonists of CaSR -- Identification of Ca2+ and PO43 binding sites in CaSR -- Universal activation mechanism of class C GPCRs Notes Animated audio-visual presentation with synchronized narration Title from title frames Restricted Access restricted to subscribers Notes Mode of access: World Wide Web Subject Amino acids -- Receptors Calcium -- Receptors Cellular signal transduction G proteins -- Receptors Binding Sites GABA-B Receptor Agonists GABA-B Receptor Antagonists Protein Conformation Receptors, Calcium-Sensing -- chemistry Receptors, Calcium-Sensing -- metabolism Receptors, GABA-B -- chemistry Receptors, GABA-B -- metabolism Receptors, G-Protein-Coupled

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