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Author McNaughton, Michael.

Title Irreversible and bivalent ligands for selected G-protein coupled receptors / Michael McNaughton
Published [Place of publication not identified] : [publisher not identified], 2002


Location Call no. Vol. Availability
 W'PONDS  615.71 Mcn/Iab  AVAILABLE
Description xxii, 230 leaves : illustrations ; 30 cm
Summary Derivatives of pharmaceutical compounds that could potentially bind irreversibly to a hypertension controlling receptor were synthesised to provide tools for studying this receptor. Also compounds that simultaneously activate two cardiovascular receptors with opposing cellular mechanisms were synthesised. This resulted in a desired partial reduction in the activity of one receptor
Notes Submitted to the Centre for Chiral and Molecular Technologies, School of Biological and Chemical Sciences of the Faculty of Science and Technology, Deakin University
Thesis (Ph.D.)--Deakin University, Victoria, 2002
Bibliography Bibliography: leaves 209-230
Subject Cardiovascular pharmacology.
Cardiovascular receptors.
Receptor-ligand complexes -- Research.
Cell receptors -- Research.
Angiotensins -- Receptors.
Synthetic drugs.
Agonists, Chemical
Genre/Form Academic theses.
Author Deakin University. School of Biological and Chemical Sciences
Deakin University. Faculty of Science and Technology.
Deakin University. Centre for Chiral Molecular Technologies