Title Irreversible and bivalent ligands for selected G-protein coupled receptors / Michael McNaughton

Published [Place of publication not identified] : [publisher not identified], 2002

Copies

Location	Call no.	Vol.	Availability
W'PONDS	615.71 Mcn/Iab		AVAILABLE

Description xxii, 230 leaves : illustrations ; 30 cm Summary Derivatives of pharmaceutical compounds that could potentially bind irreversibly to a hypertension controlling receptor were synthesised to provide tools for studying this receptor. Also compounds that simultaneously activate two cardiovascular receptors with opposing cellular mechanisms were synthesised. This resulted in a desired partial reduction in the activity of one receptor Notes Submitted to the Centre for Chiral and Molecular Technologies, School of Biological and Chemical Sciences of the Faculty of Science and Technology, Deakin University Thesis (Ph.D.)--Deakin University, Victoria, 2002 Bibliography Bibliography: leaves 209-230 Subject Cardiovascular pharmacology. Cardiovascular receptors. Hypertension. Receptor-ligand complexes -- Research. Cell receptors -- Research. Angiotensins -- Receptors. Synthetic drugs. Agonists, Chemical Genre/Form Academic theses. Author Deakin University. School of Biological and Chemical Sciences Deakin University. Faculty of Science and Technology. Deakin University. Centre for Chiral Molecular Technologies

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