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Title BLyS ligands and receptors / Michael P. Cancro, editor
Published New York : Humana Press, [2010]
Online access available from:
Springer eBooks    View Resource Record  


Description 1 online resource (xiii, 289 pages) : illustrations
Series Contemporary immunology
Contemporary immunology.
Contents The Beautiful Structures of BAFF, APRIL, and Their Receptors -- BAFF Receptor Regulation of Peripheral B-Lymphocyte Survival and Development -- Regulation of B-Cell Self-Tolerance By BAFF and the Molecular Basis of Its Action -- Role of BAFF and APRIL in Antibody Production and Diversification -- Signal Transduction by Receptors for BAFF and APRIL -- TACI Signaling and Its Role in Immunity -- The BAFF/APRIL System in Autoimmunity -- Systemic Immune-Based Rheumatic Diseases: Blissless States of BLySfulness -- The Role of BAFF and APRIL in Regulating Human B-Cell Behaviour: Implications for Disease Pathogenesis -- Translation of BAFF Inhibition from Mouse to Non-human Primate and Human -- BLyS/BR3 Receptor Signaling in the Biology and Pathophysiology of Aggressive B-Cell Lymphomas -- Tipping the Scales of Survival: The Role of BLyS in B-Cell Malignancies
Summary Centers on the BLyS(BAFF) family of ligands and receptors. This book covers basic and translational/clinical aspects of this molecular family's biology. It focuses on the BLyS family's role in the differentiation, selection, and regulation of primary and antigen-experienced B cells
Bibliography Includes bibliographical references and index
Notes Print version record
Subject Ligands (Biochemistry)
Cell receptors.
B cells.
B cells -- Differentiation.
B-Lymphocytes -- cytology.
Cell Differentiation -- immunology.
Receptors, Cell Surface -- immunology.
Form Electronic book
Author Cancro, M. P. (Michael P.)
LC no. 2009933798
ISBN 9781603270137