| Description |
1 online resource (xvi, 391 pages) : illustrations (some color) |
| Series |
Contemporary neuroscience |
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Contemporary neuroscience.
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| Contents |
Current views of the embryonic and neural stem cell : cell replacement or molecular repair? / Roya Sabetrasekh [and others] -- Developing novel cell sources for transplantation in Parkinson's disease / Nicolaj S. Christophersen [and others] -- Neural transplantation in the nonhuman primate model of Parkinson's disease / Kimberly B. Bjugstad and John R. Sladek, Jr. -- Cell-based therapy for Huntington's disease / Claire M. Kelly, Stephen B. Dunnett, and Anne E. Rosser -- Use of bone marrow stem cells as therapy for behavioral deficits in rodent models of Huntington's disease / Gary L. Dunbar, Justin D. Oh-Lee, and Laurent Lescaudron -- Human neuroteratocarcinoma cells as a neural progenitor graft source for cell transplantation in stroke / Cesario V. Borlongan [and others] |
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Therapeutic applications of bone marrow-derived stem cells in neurologic injury and disease / C. Dirk Keene [and others] -- Cell therapy for models of pain and traumatic brain injury / Mary Eaton and Jacqueline Sagen -- The use of sertoli cells in neural transplantation / Dwaine F. Emerich, Cesario V. Borlongan, and Craig Halberstadt -- The choroids plexus : a novel graft source for neural transplantation / Cesario V. Borlongan [and others] -- Progress and challenges in immunoisolation for CNS cell therapy / Christopher G. Thanos and Dwaine F. Emerich -- Evidence-based methodology for advancing neural reconstruction / Stephen Polgar -- Hematopoietic cell therapy for brain repair / Martina Vendrame and Alison E. Willing -- Stem cells and regenerative medicine : commercial and pharmaceutical implications / L. Eduardo Cruz and Silvia P. Azevedo |
| Summary |
As our world continues to evolve, the field of regenerative medicine f- lows suit. Although many modern day therapies focus on synthetic and na- ral medicinal treatments for brain repair, many of these treatments and prescriptions lack adequate results or only have the ability to slow the p- gression of neurological disease or injury. Cell therapy, however, remains the most compelling treatment for neurodegenerative diseases, disorders, and injuries, including Parkinson's disease, Huntington's disease, traumatic brain injury, and stroke, which is expanded upon in more detail in Chapter 1 by Snyder and colleagues. Cell therapy is also unique in that it is the only therapeutic strategy that strives to replace lost, damaged, or dysfunctional cells with healthy ones. This repair and replacement may be due to an administration of exogenous cells itself or the activation of the body's own endogenous reparative cells by a trophic, immune, or inflammatory response to cell transplantation. However, the precise mechanism of how cell therapy works remains elusive and is c- tinuing to be investigated in terms of molecular and cellular responses, in particular. Moreover, Chapter 11 by Emerich and associates, discusses some of the possibilities of cell immunoisolation and the potential for treating central nervous system diseases |
| Bibliography |
Includes bibliographical references and index |
| Notes |
English |
| Subject |
Cellular therapy.
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Neural stem cells.
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Brain -- Diseases -- Treatment
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Stem cells -- Transplantation.
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Brain Diseases -- therapy
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Stem Cell Transplantation
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Cell Differentiation -- physiology
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Stem Cells -- physiology
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Cell- and Tissue-Based Therapy
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HEALTH & FITNESS -- Diseases -- Nervous System (incl. Brain)
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MEDICAL -- Neurology.
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Biomédecine.
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Sciences de la vie.
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Stem cells -- Transplantation
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Brain -- Diseases -- Treatment
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Cellular therapy
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Neural stem cells
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| Form |
Electronic book
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| Author |
Sanberg, Cyndy Davis.
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|
Sanberg, Paul R.
|
| ISBN |
1588295028 |
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9781588295026 |
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9781597451475 |
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1597451479 |
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1280832371 |
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9781280832376 |
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9786610832378 |
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6610832374 |
|
