Book Cover; Title; Contents; Preface; Contributors; Assisted protein folding; Autoregulation of the heat shock response in prokaryotes; Inducible transcriptional regulation of heat shock genes: The stress signal and the unfolded protein response; Protein kinase cascades involved in heat shock protein expression and function; Thermotolerance and stress response: Possible involvement of Ku autoantigen; Genetic evidence for the roles of molecular chaperones in Escherichia coli metabolism; Genetic dissection of the Hsp70 chaperone system of yeast; Functions in development
Summary
This text covers cell biological, genetic and biochemical aspects of protein folding in cells from bacteria to man, summarizing our current knowledge of the cellular roles, regulation and the mechanism of action in this essential biological system