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Title Transforming clinical research in the United States : challenges and opportunities : workshop summary / Rebecca A. English, Yeanwoo Lebovitz, and Robert B. Giffin, rapporteurs ; Forum on Drug Discovery, Development, and Translation, Board on Health Sciences Policy, Institute of Medicine of the National Academies
Published Washington, D.C. : National Academies Press, ©2010

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Description 1 online resource (xvii, 131 pages) : illustrations (some color), color maps
Series Online access: National Academy of Sciences National Academies Press
Online access: NCBI NCBI Bookshelf
Contents Introduction -- The state of clinical research in the United States: an overview -- Challenges in clinical research -- Clinical trials in cardiovascular disease -- Clinical trials in depression -- Clinical trials in cancer -- Clinical trials in diabetes -- Building a robust clinical trials infrastructure
Summary "An ideal health care system relies on efficiently generating timely, accurate evidence to deliver on its promise of diminishing the divide between clinical practice and research. There are growing indications, however, that the current health care system and the clinical research that guides medical decisions in the United States falls far short of this vision. The process of generating medical evidence through clinical trials in the United States is expensive and lengthy, includes a number of regulatory hurdles, and is based on a limited infrastructure. The link between clinical research and medical progress is also frequently misunderstood or unsupported by both patients and providers. The focus of clinical research changes as diseases emerge and new treatments create cures for old conditions. As diseases evolve, the ultimate goal remains to speed new and improved medical treatments to patients throughout the world. To keep pace with rapidly changing health care demands, clinical research resources need to be organized and on hand to address the numerous health care questions that continually emerge. Improving the overall capacity of the clinical research enterprise will depend on ensuring that there is an adequate infrastructure in place to support the investigators who conduct research, the patients with real diseases who volunteer to participate in experimental research, and the institutions that organize and carry out the trials. To address these issues and better understand the current state of clinical research in the United States, the Institute of Medicine's (IOM) Forum on Drug Discovery, Development, and Translation held a 2-day workshop entitled Transforming Clinical Research in the United States. The workshop, summarized in this volume, laid the foundation for a broader initiative of the Forum addressing different aspects of clinical research. Future Forum plans include further examining regulatory, administrative, and structural barriers to the effective conduct of clinical research; developing a vision for a stable, continuously funded clinical research infrastructure in the United States; and considering strategies and collaborative activities to facilitate more robust public engagement in the clinical research enterprise."--Publisher's description
Bibliography Includes bibliographical references (pages 103-105)
Notes English
Print version record
Subject Clinical trials -- United States -- Congresses
Clinical trials -- Research -- United States -- Congresses
Clinical trials -- Government policy -- United States -- Congresses
Evidence-based medicine.
Drug Discovery -- Congresses -- United States
Public Policy -- Congresses -- United States
Clinical Trials as Topic -- Congresses -- United States
Clinical Trials as Topic -- United States -- Congresses
Biomedical Research -- United States -- Congresses
Research Design -- United States -- Congresses
Evidence-Based Medicine -- United States -- Congresses
Drug Discovery
Public Policy
Biomedical Research
Research Design
Evidence-Based Medicine
Clinical Trials as Topic
MEDICAL -- Research.
Evidence-based medicine
Clinical trials
Clinical trials -- Government policy
SUBJECT United States
Subject United States
Genre/Form proceedings (reports)
Conference papers and proceedings
Conference papers and proceedings.
Actes de congrès.
Form Electronic book
Author English, Rebecca A.
Lebovitz, Yeonwoo.
Giffin, Robert B.
Institute of Medicine (U.S.). Forum on Drug Discovery, Development, and Translation.
LC no. 2012405266
ISBN 9780309153331
0309153336
1282917021
9781282917026
9786612917028
6612917024
0309163358
9780309163354