Medical Research -- Searching for Answers; The Case-Control Method -- Looking Backwards; The Cohort Study -- Watchful Waiting; The Clinical Trial -The Gold Standard; Comparing the Methods -- Qualitative Differences; The Protocol -- The Guiding Light; The Control Group -- Leveling the Playing Field; Measurements -- They'ever Exact; Bias Control -- A Closer Look at Blinding and Randomization; Utility -- Are Clinical Trial Results Useful?; Research Discrimination -- Inadequately Tested Populations; Seven Deadly Flaws -- The Clinical Trials' Achilles' Heel; Statistics -- Was the Finding Significant?
Analysis Issues -- A Lot of ChoicesMeta Analysis -- An Alternative to Large Trials; Research Results That Clashed -- What's the Right Answer?; Hormone Replacement Therapy -- The Silver Bullet That Misfired; Publishing -- Getting the Word Out to Doctors; The Public Forum -- Sharing the News with the Public; Product Development -- Getting Discoveries to the Market; Medical Innovations -- Regulators, Resources and Results; Science and Politics -- A Troubling Mixture; Research Misconduct -- Irresistible Temptation; Postmarketing Surveillance -- An Imperfect System; Regulatory Reform -- Changes Needed
Journey's End -- A Call for Action
Summary
Dissects medical research methodology and through an inquiry into its triumphs and tragedies explains why correct answers are so hard to achieve. This book teaches readers why the quest for knowledge through clinical trials is fraught with problems that even the best researchers cannot overcome
Analysis
geneeskunde
medicine
gezondheid
health
volksgezondheid
public health
epidemiologie
epidemiology
biomedische wetenschappen
biomedicine
levenswetenschappen
life sciences
toegepaste statistiek
applied statistics
Medicine (General)
Geneeskunde (algemeen)
Bibliography
Includes bibliographical references (pages 255-281) and index
