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Title Cystic fibrosis in the 21st century / volume editors, Andrew Bush [and others]
Published Basel ; New York : Karger, 2006
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Description 1 online resource (ix, 329 pages) : illustrations (some color)
Series Progress in respiratory research, 1422-2140 ; v. 34
Progress in respiratory research ; v. 34. 1422-2140
Contents The CFTR gene: structure, mutations and specific therapeutic approaches / Nissim-Rafinia, M., Linde, L., Kerem, B. -- Exquisite and multilevel regulation of CFTR expression / Trezise, A.E.O. -- Intracellular processing of CFTR / Barriere, H., Lukacs, G.L. -- Structure of the cystic fibrosis transmembrane conductance regulator / Stratford, F.L.L., Bear, C.E. -- Function of CFTR protein: ion transport / Chen, J.-H. [and others] -- Cystic fibrosis. Function of CFTR Protein: regulatory functions / Coakley, R.D., Stutts, M.J. -- Function of CFTR protein: developmental role / Gill, D., Larson, J.E. -- Genotype-phenotype correlations in cystic fibrosis / Dorfman, R., Zielenski, J. -- Diagnosis of cystic fibrosis, CFTR-related disease and screening / Karczeski, B.A., Cutting, G.R. -- CF modifier genes / Griesenbach, U., Alton, E.W.F.W., Davies, J.C. -- Animal models / Dorin, J.R -- In vitro/ex vivo fluorescence assays of CFTR chloride channel function / Verkman, A.S., Galietta, L.J.V. -- In vivo measurement of airway potential difference to assess CFTR function in man / Middleton, P., Alton, E.W.F.W. -- Arrays and proteomics / Ogilvie, V.C., MacGregor, G. -- Pathogenesis of pulmonary disease in cystic fibrosis / Mall, M., Boucher, R.C. -- Infection versus inflammation / Ziady, A.G., Davis, P.B. -- Pseudomonas aeruginosa: clinical research / Armstrong, D. -- Pseudomonas aeruginosa: basic research / Scott, F.W., Pitt, T.L. -- Other gram-negative organisms: Burkholderia cepacia complex and Stenotrophomonas maltophilia / Govan, J.R.W. -- Staphylococcus aureus and MRSA / Conway, S., Denton, M. -- Nontuberculous mycobacterial lung disease in patients with cystic fibrosis / Griffith, D.E -- Respiratory fungal infections and allergic bronchopulmonary aspergillosis / Que, C., Geddes, D. -- Advanced disease management and advances in transplant medicine / Carby, M.R., Hodson, M.E. -- Current and novel antimicrobial approaches / Davies, J.C. -- Anti-inflammatory agents: a clinical perspective / Hilliard, T.N., Balfour-Lynn, I.M. -- Recent advances in infant and pre-school lung function / Ranganathan, S. -- Recent advances in imaging / Oikonomou, A., Hansell, D.M. -- New pharmacological approaches for treatment of cystic fibrosis / Rubenstein, R.C. -- Gene and stem cell therapy / Boyd, A.C. -- Gut disease: clinical manifestations, pathophysiology, current and new treatments / Taylor, C.J., Hardcastle, J. -- Pancreatic involvement: clinical manifestations, pathophysiology and new treatments / Lindley, K.J. -- Cystic fibrosis: liver disease / Westaby, D. -- Fertility, contraception, incontinence and pregnancy / Thorpe-Beeston, J.G. -- Arthritis, vasculitis and bone disease / Elkin, S. -- Diabetes in cystic fibrosis / Bridges, N., Spowart, K. -- Challenges for nurses / Madge, S. -- Dietetics / Wolfe, S., Morton, A. -- Physiotherapy / Pryor, J.A. [and others] -- Psychological interventions / Bryon, M. -- The future / Bush, A. [and others]
Summary Cystic fibrosis used to be thought of as a respiratory and digestive disease, with a uniformly and rapidly fatal outcome. The spectrum of the disease has broadened into the mild atypical case, presenting in middle age, with the potential for complications in virtually every system of the body. In the past few years there has been an explosion of knowledge of the basic science of the defect. The editors have therefore invited the leading scientists and clinicians in the field of cystic fibrosis to describe the recent advances in this disease. Although there are many 'Recent Advances' texts, pre
Bibliography Includes bibliographical references and indexes
Notes Print version record
Subject 2000s
Cystic Fibrosis -- complications.
Cystic Fibrosis -- genetics.
Cystic Fibrosis Transmembrane Conductance Regulator -- genetics.
Cystic Fibrosis Transmembrane Conductance Regulator -- metabolism.
Lung -- physiopathology.
Cystic fibrosis -- Genetic aspects.
Cystic fibrosis.
Form Electronic book
Author Bush, Andrew, 1954 April 24-
ISBN 1423796802 (electronic bk.)
3318012408
9781423796800 (electronic bk.)
9783318012408
(hard cover ; alk. paper)
Other Titles Cystic fibrosis in the twenty-first century