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Book Cover
Author Drăghici, Sorin.

Title Data analysis tools for DNA microarrays / Sorin Draghici
Published Boca Raton, Fla. : Chapman & Hall/CRC, [2003]


Location Call no. Vol. Availability
 W'PONDS  572.8636 Dra/Dat  AVAILABLE
Description 477 pages : illustrations (chiefly color) ; 24 cm + 2 CD-ROMS (4 3/4 in)
4 3/4 in
Series Chapman & Hall/CRC mathematical biology and medicine series
Chapman & Hall/CRC mathematical biology and medicine series.
Contents 1. Introduction -- 2. Microarrays -- 3. Image processing -- 4. Elements of statistics -- 5. Statistical hypothesis testing -- 6. Classical approaches to data analysis -- 7. Analysis of Variance - ANOVA -- 8. Experiment design -- 9. Multiple comparisons -- 10. Analysis and visualization tools -- 11. Cluster analysis -- 12. Data pre-processing and normalization -- 13. Methods for selecting differentially regulated genes -- 14. Functional analysis and biological interpretation of microarray data -- 15. Focused microarrays - comparison and selection -- 16. Commercial applications -- 17. The road ahead
Summary "The theoretical aspects are complemented by a discussion of several commercial applications with sections exploring various software packages from BioDiscovery, Insightful, SAS, and Spotfire. The book is illustrated with more than 230 figures in full color. The attached CD-ROMs contain full-feature trial versions of leading software for image and data analysis allowing the reader to practice everything explained in the book."--BOOK JACKET. "Data Analysis Tools for DNA Microarrays builds the foundation in the statistics and data analysis tools needed by biologists and provides the overview of microarrays needed by computer scientists. Describing the most complex data analysis techniques in simple language, this book aims to lower the communication barrier between life scientists and analytical scientists. The book explains complex and sometimes subtle data analysis issues providing the life scientist with the ability to make informed choices in the day-by-day exploratory data analysis. For the analytical scientist, the book explains the most common biological questions and emphasizes specific data analysis issues characteristic of microarray data."
Bibliography Includes bibliographical references (pages 443-465) and index
Notes Minimum system requirements: MS Windows 98, 2000, ME, NT 4 x, or XP; hardrive requirements: Pentium III processor or higher; 64 MB RAM; Hard drive with 512-MB of available disk space; CD-ROM drive (4x); SVGA monitor of 800x600, 256 colors
Subject DNA microarrays -- Mathematical models.
DNA microarrays -- Methodology.
DNA microarrays -- Statistical methods.
Oligonucleotide Array Sequence Analysis -- methods.
Oligonucleotide Array Sequence Analysis -- statistics & numerical data.
LC no. 2003046077
ISBN 1584883154 paperback alkaline paper