Title DNA methylation : basic mechanisms / W. Doerfler and P. Böhm, eds

Published Berlin ; New York : Springer, ©2006

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Description 1 online resource (vi, 321 pages) : illustrations Series Current topics in microbiology and immunology, 0070-217X ; 301 Current topics in microbiology and immunology ; 301. 0070-217X Contents The Almost-Forgotten Fifth Nucleotide in DNA: An Introduction -- Pattern Formation -- Replication and Translation of Epigenetic Information -- DNA Methyltransferases: Facts, Clues, Mysteries -- DNA Methylation in Plants -- Determinant of Promoter Activity -- De Novo Methylation, Long-Term Promoter Silencing, Methylation Patterns in the Human Genome, and Consequences of Foreign DNA Insertion -- DNA Methyltransferases -- Establishment and Maintenance of DNA Methylation Patterns in Mammals -- Molecular Enzymology of Mammalian DNA Methyltransferases -- Epigenetic Phenomena -- Familial Hydatidiform Molar Pregnancy: The Germline Imprinting Defect Hypothesis? -- Dual Inheritance -- Mutagenesis and Repair -- Mutagenesis at Methylated CpG Sequences -- Cytosine Methylation and DNA Repair Summary The structural and functional importance of the correct patterns of DNA methylation in all parts of a mammalian genome is not well understood. The stability, inheritability, and developmental flexibility of these patterns point to a major role that these patterns appear to play in determining structure and function of the genome Bibliography Includes bibliographical references and index Notes Print version record In Springer e-books Subject DNA -- Methylation DNA Methylation SCIENCE -- Life Sciences -- Genetics & Genomics. DNA Methylation. DNA -- Methylation. Biomédecine. Sciences de la vie. DNA -- Methylation Form Electronic book Author Doerfler, Walter, 1933- Böhm, P. (Petra) ISBN 9783540313908 3540313907 6610462607 9786610462605

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