| Description |
1 online resource |
| Series |
BIOSCIENCEnetBASE
|
| Contents |
Epigenetics and cancer: DNA methylation / Santiago Ropero and Manel Esteller -- Epigenetics and cancer: histone modifications / Mario F. Fraga and Manel Esteller -- Epigenetic drugs: DNA demethylating agents / Ehab Atallah, Guillermo Garcia-Manero -- Epigenetic drugs: histone deacetylase inhibitors / Melissa Peart, Ricky W. Johnstone -- Sirtuins in biology and disease / Alejandro Vaquero, Danny Reinberg -- MicroRNAs in cell biology and disease / Muller Fabbri, Carlo M. Croce, George A. Calin -- Chromatin modifications by polycomb complexes / Miguel Vidal -- Epigenetics and its genetic syndromes / Richard J. Gibbons -- Epigenetics and immunity / Esteban Ballestar and Bruce C. Richardson -- Aetiology of major psychosis: why do we need epigenetics? / Gabriel Oh and Arturas Petronis -- Epigenetics and cardiovascular disease / Gertrund Lund and Silvio Zaina -- Epigenetics and plant biology / Luis Valledor [and others] -- Epigenetics, environment, and evolution / Douglas M. Ruden, Parsa Rasouli, Xiangyi Lu -- Epigenetics and epigenomics / José Ignacio Martín-Subero, Reiner Siebert |
| Summary |
Epigenetic changes are essential to normal development, but these changes can also cause problems including the disabling of genes that suppress tumors. At present more than a dozen drugs that target epigenetic changes are in clinical trials. "Epigenetics in Biology and Medicine" offers a comprehensive overview of epigenetics, both in normal functions and disease states. This book presents contributions from international experts, addressing both theoretical and methodological issues. It discusses cell biology and the role of epigenetics in human, animal, and plant diseases. The text also covers DNA methylation inhibitors, histone modifications, and epigenomics, as well as the impact that diet has on epigenetic changes |
| Bibliography |
Includes bibliographical references and index |
| Notes |
Print version record |
| Subject |
DNA -- Methylation
|
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Histones.
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Epigenesis.
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Carcinogenesis.
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Epigenesis, Genetic
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Histones
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Carcinogenesis
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SCIENCE -- Life Sciences -- Genetics & Genomics.
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Carcinogenesis
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DNA -- Methylation
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Epigenesis
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Histones
|
| Form |
Electronic book
|
| Author |
Esteller, Manel.
|
| ISBN |
9781420007077 |
|
1420007076 |
|
9780849372896 |
|
0849372895 |
|
