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Title DNA conformation and transcription / [edited by] Takashi Ohyama
Published Georgetown, Tex. : Landes Bioscience/Eurekah.com ; New York : Springer Science+Business Media, [2005]
©2005
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Description 1 online resource (211 pages) : illustrations (some color)
Series Molecular biology intelligence unit
Molecular biology intelligence unit (Unnumbered)
Contents DNA: alternative conformations and biology / Vladimir N. Potaman and Richard R. Sinden -- Sequence-dependent variability of B-DNA: an update on bending and curvature / Victor B. Zhurkin [and others] -- Curved DNA and prokaryotic promoters: a mechanism for activation of transcription / Munehiko Asayama and Takashi Ohyama -- Repression of transcription by curved DNA and nucleoid protein H-NS: a mode of bacterial gene regulation / Cynthia L. Pon, Stefano Stella and Claudio O. Gualerzi -- Curved DNA and transcription in eukaryotes / Takashi Ohyama -- Putative roles of kin17, a mammalian protein binding curved DNA, in transcription / Jaime F. Angulo [and others] -- Roles for Z-DNA and double-stranded RNA in transcription: encoding genetic information by shape rather than by sequence / Alan Herbert -- Do DNA triple helices or quadruplexes have a role in transcription? / Michael W. Van Dyke -- Nucleic acid structures and the transcription defects in fragile X syndrome and Friedreich's ataxia / Karen Usdin -- Possible roles of DNA supercoiling in transcription / Susumu Hirose and Kuniharu Matsumoto -- Gene regulation by HMGA and HMGB chromosomal proteins and related architectural DNA-binding proteins / Andrew A. Travers -- Molecular mechanisms of male sex determination: the enigma of SRY / Michael A. Weiss -- The role of unusual DNA structures in chromatin organization for transcription / Takashi Ohyama -- DNA bendability and nucleosome positioning in transcriptional regulation / Mensur Dlakić, David W. Ussery and Søren Brunak
Summary Annotation Despite remarkable progress in genome science, we are still far from a clear understanding of how genomic DNA is packaged without entanglement into a nucleus, how genes are wrapped up in chromatin, how chromatin structure is faithfully inherited from mother to daughter cells, and how the differential expression of genes is enabled in a given cell type. Exploring and answering these questions constitutes one of the next frontiers in the 21st century. We are just beginning to appreciate how Multifarious DNA structures provide additional structural and functional dimensions to chromatin organization and gene expression. DNA Conformation and Transcription is the first book that compiles the fruits of the studies that have been performed to date to solve the riddle 'written' in DNA conformation ("conformation code"). This book provides a comprehensive overview of the field by covering history of the field, up-to-date topics, clarifications of present day research, and future perspective of what is still to be discovered. Thus, it serves as an invaluable source of information on the "conformation code."
Bibliography Includes bibliographical references and index
Notes Print version record
In Springer e-books
Subject DNA -- Conformation.
Genetic transcription.
DNA -- chemistry.
DNA -- metabolism.
Nucleic Acid Conformation.
Transcription, Genetic.
Form Electronic book
Author Ohyama, Takashi.
LC no. 2005012636
ISBN 0387255796
0387291482
1423724038 (electronic bk.)
9780387255798
9780387291482
9781423724032 (electronic bk.)