| Description |
1 online resource (xviii, 564 pages) : illustrations |
| Series |
Contemporary diabetes |
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Contemporary diabetes.
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| Contents |
Angiotensin II and its receptors in the pathogensis of diabetic nephropathy / David J. Leehey, Ashok K. Singh, and Rekha Singh -- Altered renal microvasculature function in early diabetes / Pamela K. Carmines, Joseph P. Bast, and Naohito Ishii -- Proteinuria and interstitial fibrogenesis in diabetic nephropathy / Raimund Hirschberg -- Podocytes and diabetic nephropathy / George Jerums, Sianna Panagiotopoulos, and Richard MacIsaac -- Altered glucose transport and its metabolic effects in glomerular cells / Charles W. Heilig -- mRNA translation in diabetic nephropathy / Balakuntalam S. Kasinath [and others] -- The hexosamine biosynthesis pathway: contribution to the pathogenesis of diabetic nephropathy / I. George Fantus [and others] -- Glycation: receptor for advanced glycation endproducts and diabetic nephropathy / Vivette D'Agati and Ann Marie Schmidt -- Oxidative and glycooxidative stress in diabetic nephropathy / Frederick R. DeRubertis and Patricia A. Craven |
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Connective tissue growth factor in the pathogenesis of diabetic nephropathy: a target for therapeutic intervention / Bruce L. Riser, Alessia Fornoni, and Sujatha Karoor -- Vascular endothelial growth factor as a determinant of diabetic nephropathy / Geoffrey Boner and Mark E. Cooper -- Transforming growth factor-€ signal transduction in the pathogenesis of diabetic nephropathy: identifying molecular targets for therapeutic intervention / Sheldon Chen and Fuad N. Ziyadeh -- Hepatocyte growth factor: physiological and therapeutic ligand to attenuate diabetic nephropathy / Shinya Mizuno and Toshikazu Nakamura -- Proteomics in the investigation of diabetic nephropathy / Visith Thongboonkerd -- Gene expression profiling in the investigation of diabetic nephropathy / Katalin Susztak, Erwin Bottinger, and Kumar Sharma -- PPAR- ligands and diabetic nephropathy / Keiji Isshiki, Daisuke Koya, and Masakazu Haneda -- -Endosulfine in diabetic nephropathy / Jerry Yee and Balazs Szamosfalvi |
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The prospect of a novel therapeutic, bone morphogenetic protein-7, in diabetic nephropathy / Keith A. Hruska [and others] -- Genetic determinants of diabetic nephropathy in type 2 diabetes / Grzegorz Placha and Andrzej S. Krolewski -- Major risk indicators for diabetic kidney disease / Katherine R. Tuttle -- The structure of human diabetic nephropathy / Michael Mauer and Behzad Najafian -- Diabetic kidney disease in transitional and disadvantaged populations / E. Jennifer Weil and Robert G. Nelson -- Screening and treatment of early diabetic renal disease in type 1 and type 2 diabetes / Ellie Chuang and Mark E. Molitch -- Treatment in advanced renal disease in type 1 and type 2 diabetes / Eberhard Ritz and Gunter Wolf -- Diabetic and renal disease: ACE inhibitors and/or angiotensin receptor blockers: does it matter? / Carl Erik Mogensen and Niels Holmark Andersen -- Management of diabetic end-stage renal disease with dialysis / Ploumis S. Passadakis and Dimitrios G. Oreopoulos -- Diabetic retinopathy and nephropathy / Ronald Klein -- Hypertension and cardiovascular disease / Adam Whaley-Connell, Kurt Sowers, and James R. Sowers -- Endothelial dysfunction and diabetic nephropathy / Coen D.A. Stehouwer [and others] -- Anemia and diabetic nephropathy / George Jerums [and others] |
| Summary |
Although diabetic kidney disease is the most prevalent cause of end-stage renal disease and the disease most often leading to chronic renal replacement therapy and kidney transplantation, there has been, in recent years, a steady increase in basic and clinical knowledge of the problem. In The Diabetic Kidney, a stellar group of international researchers and clinicians joins forces to independently survey recent findings, ideas, and hypotheses about the causes and treatment of diabetic nephropathy. Drawing on many years of experience, the authors cover both the basic pathogenic mechanisms of the disease, as well as many of its clinical aspects of identification, management, and new therapeutic approaches. Not always in total agreement, their views reflect the present state of knowledge and its uncertainties, and offer a composite of different authoritative views on the causes of diabetic kidney disease. Highlights include an entire section devoted to novel approaches to studying diabetic nephropathy with the most advanced molecular techniques, and comprehensive descriptions of the most up-to-date views on the diagnosis and treatment of the disease. State of the art and illuminating, The Diabetic Kidney offers both researchers and practicing clinicians a clear understanding of the progress that has been made regarding the pathogenesis of diabetic nephropathy and of the therapeutic interventions needed to prevent its development or treat it |
| Bibliography |
Includes bibliographical references and index |
| Notes |
English |
| In |
Springer e-books |
| Subject |
Diabetic nephropathies.
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Diabetes.
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Diabetic Nephropathies -- physiopathology
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Diabetes Mellitus -- diagnosis
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Diabetes Mellitus -- therapy
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Diabetic Nephropathies
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Diabetes Mellitus
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MEDICAL -- Nephrology.
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Diabetes.
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Diabetic Nephropathies -- physiopathology.
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Diabetes Mellitus -- diagnosis.
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Diabetes mellitus -- Therapy.
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Néphropathies diabétiques.
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Diabète.
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Diabetic nephropathies.
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Diabetes
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Diabetic nephropathies
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| Form |
Electronic book
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| Author |
Cortes, Pedro.
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Mogensen, Carl Erik.
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| ISBN |
1588296245 |
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1597451533 |
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9781597451536 |
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9781588296245 |
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1280832436 |
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9781280832437 |
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9786610832439 |
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6610832439 |
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