| Description |
1 online resource (xi, 281 pages) : illustrations |
| Contents |
Cover -- Half-title -- Title page -- Copyright information -- Contents -- List of Contributors -- Preface -- 1 Fundamentals on Synthesis and Properties of Ultrananocrystalline Diamond (UNCD™) Coatings -- 1.1 Background on UNCD Film Synthesis, Properties, and Applications -- 1.2 Fundamentals of UNCD Film Synthesis via MPCVD and Properties -- 1.2.1 Fundamentals on the Synthesis of MCD, NCD, and UNCD Thin Films via MPCVD with the Chemical Seeding Process -- 1.2.1.1 MPCVD Growth Process for MCD and NCD Films with the Wet Seeding Process -- 1.2.1.2 MPCVD Growth Process for UNCD Films with the Conventional Wet Seeding Process -- Growth, Structure, and Chemical Characterization of Insulating UNCD Films -- Growth Process. -- Structure Characterization. -- Chemical Characterization. -- 1.2.1.3 MPCVD Growth Process for UNCD Films via the BEN-BEG Process -- Background on MPCVD BEN-BEG of MCD and NCD Films -- MPCVD BEN-BEG of UNCD Films -- 1.2.1.4 MPCVD Growth and Structure and Chemical Characterization of Electrically Conductive UNCD Films with Boron Atoms Replacing C Atoms in the UNCD Diamond Grains Forming B-UNCD Films or Nitrogen Atoms Inserted in Grain Boundaries Forming N-UNCD Films -- Background on High-Tech and Bio-related Applications of Electrically Conductive B-UNCD and N-UNCD Films -- Doping of UNCD Films with Boron (B) Atoms to Produce B-UNCD Films -- Background on Research to Produce n-Type Electrically Conductive Diamond Films for Biomedical Applications -- Growth and Characterization of N-UNCD Films for Implantable Biocompatible Electrically Conductive Electrodes and Other Electronic Devices -- Growth of N-UNCD Films via the MPCVD Plus Chemical Seeding Process -- Electrical Conductivity -- Electron Field Emission -- Growth of N-UNCD Films by MPCVD via the BEN-BEG Process |
|
1.3 Fundamentals on the Synthesis of MCD, NCD, and UNCD Thin Films via HFCVD -- 1.3.1 Background Information on the Need for HFCVD to Grow PCD Films -- 1.3.2 Fundamentals and Properties of UNCD Films Grown by HFCVD -- 1.3.2.1 Background Information on Prior Research on HFCVD-Grown Diamond Films -- 1.3.2.2 Fundamentals on Synthesis and Characterization of PCD Films By Chemical Seeding Plus HFCVD Growth Process -- 1.3.2.3 Fundamentals on Synthesis and Characterization of MCD, NCD, and UNCD Films on HfO2 Films on Si by Chemical Seeding Plus HFCVD Growth Process -- Background on the Importance of Growing MCD to UNCD Films on HfO2 Films for Biomedical and Other Devices Based on Si -- Synthesis and Characterization of MCD, NCD, and UNCD Films on HfO2 Films on Si -- Diamond Film Growth. -- Characterization of Diamond Films Structure by Electron Microscopy. -- Chemical Analysis of UNCD Films. -- 1.3.2.4 Fundamentals on Synthesis and Characterization of UNCD Films with Tailoring of the UNCD Surface from Super-Hydrophilic to Super-Hydrophobic for Multifunctional External and Implantable Medical Devices and Prostheses: Background for Application of Super-Hydrophobic to Super-Hydrophilic UNCD Coating surfaces -- Cardiovascular and Other Blood-Interfacing Devices. -- Other Devices Benefiting from Tailoring of Surface Wettability. -- Fundamentals on the Synthesis and Characterization of Super-Hydrophobic to Super-Hydrophilic UNCD Coatings Using Chemical Seeding plus HFCVD Process -- Background on Research on Wettability of Diamond Surfaces -- Growth of UNCD Films by Chemical Seeding Plus HFCVD Process -- Treatment of PCD Films Surfaces with O2, H2, and CF4 Plasmas to Tailor Wettability and Characterization -- Characterization of Key Parameters of the Treated Surfaces of UNCD Films to Produce Super-hydrophilic to Super-Hydrophobic Surfaces |
|
1.3.2.5 Fundamentals on Synthesis and Characterization of PCD Films By the HFCVD-Based BEN-BEG Process -- Background on HFCVD BEN-BEG of Diamond Films -- Fundamentals and Technological Development of HFCVD BEN-BEG of UNCD Films -- XRD Analysis. -- SEM Analysis. -- HRTEM Studies. -- EELS Analysis. -- EDAX Analysis. -- Studies of UNCD/W Layer Interfaces via Cross-Section HRTEM. -- XPS Analysis of UNCD Films. -- Complementary Experiment and Modeling of HFCVD BEN-BEG of UNCD Films. -- Selective Growth of UNCD Films on W-Patterned Layers on a Si Substrate. -- Conclusions on the HFCVD BEN-BEG Process -- 1.4 Conclusions -- 2 Ultrananocrystalline Diamond (UNCD™) Film as a Hermetic Biocompatible/Bioinert Coating for Encapsulation of an Eye-Implantable Microchip to Restore Partial Vision to Blind People -- 2.1 Background Information on Vision, Conditions that Induce Blindness in Humans Born with Vision, and Concepts for Artificial Retina Devices to Restore Partial Vision -- 2.1.1 Human Image (Vision) Formation -- 2.1.2 Retinitis Pigmentosa -- 2.2 Vision Restoration Technologies -- 2.2.1 Gene-Based Retinal Degeneration Therapies -- 2.2.2 Electronic Retinal Prostheses-Based Retinal Degeneration Therapies -- 2.2.3 Argus II Retinal Prosthesis -- 2.3 Scientific and Technological State-of-the-Art of Biocompatible/Bioinert Encapsulation Technologies for Si Microchips Implantable in the Eye -- 2.3.1 Process and Design Considerations for Hermetic/Biocompatible/Bioinert Encapsulants for Implantable Si Microchips (Artificial Retina) -- 2.3.2 Materials Previously Investigated for Biocompatible/Hermetic Encapsulating Coatings for Implantable Microchips -- 2.4 Carbon-Based Biocompatible UNCD Coating for Si Microchip Encapsulation and Growth Techniques -- 2.5 Characterization of Hermetic/Biocompatible/Corrosion-Resistant/ Bioinert Si Microchip-Encapsulating UNCD Coating |
|
2.5.1 Characterization of Chemical, Microstructural, and Morphological Properties of UNCD Coatings -- 2.5.1.1 Raman Analysis of Polycrystalline Diamond Films -- 2.5.1.2 SEM, LRTEM, and HRTEM Analysis of Polycrystalline Diamond Films -- 2.6 Characterization of Electrochemical Performance in Eye Humor-Like Saline Solution to Test Corrosion-Resistance of Hermetic UNCD Encapsulating Coating on Silicon -- 2.7 Characterization of UNCD/CMOS Integration -- 2.8 In-Vivo Animal Tests of Hermetic/Biocompatible/Corrosion-Resistant UNCD Coatings Encapsulating Si Microchips for Artificial Retinas -- 2.9 Challenges for Bioinert Microchip Encapsulation Hermetic Coatings -- 2.10 Conclusions and Future Outlook -- 3 Science and Technology of Ultrananocrystalline Diamond (UNCD™) Coatings for Glaucoma Treatment Devices -- 3.1 Introduction -- 3.1.1 Glaucoma Condition -- Glaucoma Process. -- Glaucoma Conditions and Symptoms. -- Risk Issues Related to Glaucoma. -- 3.1.2 Prevention to Stop or Delay Glaucoma Development Until Positive Treatment Implementation -- 3.1.3 Current Glaucoma Treatments -- 3.1.4 New Glaucoma Eye Drops on the Horizon -- 3.1.5 Selective Laser Trabeculoplasty Treatment -- 3.1.6 Flexible Glaucoma Drainage Device -- Ahmed Device vs. Baerveldt Shunt. -- 3.2 Low-Cost, Best Biocompatible, Extremely Hydrophobic, and Antifouling UNCD Coating for Encapsulation of Commercial Polymer-Based Glaucoma Valves for Orders of Magnitude Performance Improvement -- 3.3 Alternative Low-Cost, Best Biocompatible, Extremely Hydrophobic, and Antifouling UNCD-Coated Mesh Implantable in the Trabecular Region of the Eye to Drain Fluid -- 3.4 Conclusions -- 4 Science and Technology of Novel Integrated Biocompatible Superparamagnetic Oxide Nanoparticles Injectable in the Human Eye and External Ultrananocrystalline Diamond (UNCD™)-Coated Magnet for a New Retina Reattachment Procedure |
|
4.1 Introduction -- 4.1.1 Biology and Function of the Human Eye and the Retina -- 4.1.2 Retina Trauma (Detachment): Symptoms and Current Treatments -- 4.1.2.1 Retina's Detachment Processes -- 4.1.2.2 Signs and Symptoms Associated with Retinal Detachment -- 4.1.2.3 Risk Factors and Prevention of Retinal Detachment -- 4.1.2.4 Diagnosis of Retinal Detachment -- 4.1.2.5 Current Treatment of Retinal Detachment -- Vitrectomy. -- Results of Surgery. -- 4.2 New Revolutionary Nanotechnology-Based Retina's Reattachment Procedure -- 4.2.1 Materials and Methods -- 4.2.1.1 Superparamagnetic Iron Oxide (Fe3O4) Nanoparticles (SPION-Fe3O4) -- Summary of R& -- D and Biomedical Use of SPION-Fe3O4 -- Fabrication and Characterization of SPION-Fe3O4 -- Characterization of Magnetic Properties of Magnets -- 4.2.2 In-Vivo Animal Studies for SPION-Fe3O4-based Retina Reattachment -- 4.2.2.1 Surgically Induced Retina's Detachment -- 4.2.2.2 Magnet Attachment on External Wall of the Eye and SPION-Fe3O4 Solution Injection into the Eye for Retina Reattachment -- Results from Animal Retina Reattachment Studies via Combined Magnetic Field Created by a Magnet on the Eye's Outer Wall and Injection of SPION-Fe3O4 Solution into the Eye -- Retinography and OCT Analysis of Retinas with Adhered SPION-Fe3O4 -- 4.2.2.3 Histological Evaluation of the Animals' Retinas Exposed to SPION-Fe3O4 Nanoparticles and Magnets Coated with Gold -- 4.2.3 In-Vivo Human Clinical Trials for SPION-Fe3O4-Based Retina Reattachment -- 4.3 Conclusions -- 5 Science and Technology of Biocompatible Ultrananocrystalline Diamond (UNCD™) Coatings for a New Generation of Implantable Prostheses: First Application to Dental Implants and Artificial Hips -- 5.1 Background Information on Human Teeth, the Need for Natural Teeth Replacement by Dental Implants, and Current Dental Implant Technologies |
| Summary |
"A comprehensive guide to the science of a transformational ultrananocrystalline-diamond (UNCDTM) thin film technology enabling a new generation of high-tech and external and implantable medical devices. Edited and coauthored by a co-originator and pioneer in the field, it describes the synthesis and material properties of UNCDTM coatings and multifunctional oxide/nitride thin films and nanoparticles, and how these technologies can be integrated into the development of implantable and external medical devices and treatments of human biological conditions. Bringing together contributions from experts around the world, it covers a range of clinical applications, including ocular implants, glaucoma treatment devices, implantable prostheses, scaffolds for stem cell growth and differentiation, Li-ion batteries for defibrillators and pacemakers, and drug delivery and sensor devices. Technology transfer and regulatory issues are also covered"-- Provided by publisher |
| Bibliography |
Includes bibliographical references and index |
| Notes |
Description based on online resource; title from digital title page (viewed on July 19, 2022) |
| Subject |
Medical instruments and apparatus -- Materials
|
|
Diamond thin films -- Industrial applications
|
|
Nanodiamonds -- Industrial applications
|
|
Diamond powder -- Industrial applications
|
|
Protective coatings.
|
|
protective coating.
|
|
Diamond thin films -- Industrial applications.
|
|
Protective coatings.
|
| Form |
Electronic book
|
| Author |
Auciello, Orlando, 1945- editor.
|
| LC no. |
2021029136 |
| ISBN |
9781316105177 |
|
1316105172 |
|
