| Description |
1 online resource (x, 474 pages) : illustrations |
| Series |
Handbook of experimental pharmacology, 0171-2004 ; v. 209 |
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Handbook of experimental pharmacology ; v. 209. 0171-2004
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| Contents |
Part 1. The neuroendocrine, hypothalamic circuitry regulating hunger, satiety, and energy expenditure. Leptin Receptors / Elizabeth C. Cottrell, Julian G. Mercer -- The Role of Neuropeptide Y in Energy Homeostasis / Adam P. Chambers, Stephen C. Woods -- The Neuroendocrine Circuitry Controlled by POMC, MSH, and AGRP / Heike Biebermann, Peter Kühnen, Gunnar Kleinau, Heiko Krude -- Neuropeptides Controlling Energy Balance: Orexins and Neuromedins / Joshua P. Nixon, Catherine M. Kotz, Colleen M. Novak, Charles J. Billington -- The Central Insulin System and Energy Balance / Denovan P. Begg, Stephen C. Woods -- Peripheral Signals Modifying Food Reward / John R.W. Menzies, Karolina P. Skibicka, Emil Egecioglu, Gareth Leng -- Part 2. Gastrointestinal hormones and factors. The Role of Ghrelin in the Control of Energy Balance / Henriette Kirchner, Kristy M. Heppner, Matthias H. Tschöp -- Anorexigenic Effects of GLP-1 and Its Analogues / Baptist Gallwitz -- CCK, PYY and PP: The Control of Energy Balance / K. Simpson, J. Parker, J. Plumer, S. Bloom -- Effects of Amylin on Eating and Adiposity / Thomas Alexander Lutz -- Intestinal Microbiota and Obesity / Michael Blaut, Susanne Klaus -- Part 3. Nutrient sensing. Sensing of Glucose in the Brain / Bernard Thorens -- Role of CD36 in Oral and Postoral Sensing of Lipids / M. Chevrot, C. Martin, P. Passilly-Degrace, P. Besnard -- Intestinal Sensing of Nutrients / Gwen Tolhurst, Frank Reimann, Fiona M. Gribble -- Part 4. Agents modifying food intake. Reuptake Inhibitors of Dopamine, Noradrenaline, and Serotonin / Ulrich Kintscher -- 5-HT2C Receptor Agonists and the Control of Appetite / Jason C.G. Halford, Joanne A. Harrold -- Central and Peripheral Cannabinoid Receptors as Therapeutic Targets in the Control of Food Intake and Body Weight / Stefan Engeli -- Antiobesity Effects of Melanin-Concentrating Hormone Receptor 1 (MCH-R1) Antagonists / Hyae Gyeong Cheon -- Appetite-Modifying Effects of Bombesin Receptor Subtype-3 Agonists / Ishita Deb Majumdar, H. Christian Weber -- Weight-Reducing Side Effects of the Antiepileptic Agents Topiramate and Zonisamide / J. Antel, J. Hebebrand |
| Summary |
Annotation The volume Appetite Control provides a comprehensive description of the mechanisms controlling food intake, and thereby energy balance, in the mammalian organism. During the last decade, research in this area has produced a remarkable wealth of information and has characterized the function of numerous peptides, transmitters, and receptors in appetite control. Dysfunction of these circuits leads to obesity, a growing health concern. However, the plethora of mechanistic information is in marked contrasts to an almost complete lack of anti-obesity drugs that meet the safety standards required for the chronic therapy of morbid obesity. Consequently, ongoing research aims to identify additional targets and agents for a pharmacological intervention. Thus, the mechanisms of appetite control as well as all agents interfering with its control are of considerable practical interest. The authors of the volume are distinguished scientists who are leading experts in the field, and who have contributed important, original data to our understanding of the mechanisms of appetite control. They have quite different scientific backgrounds and, together, they represent all relevant disciplines. Thereby, the topics are presented from different points of view, not exclusively from that of pharmacology and neuroendocrinology. Thus, the volume addresses all scientists who are interested in the field of obesity research and the pathophysiology of appetite control |
| Bibliography |
Includes bibliographical references and index |
| Subject |
Appetite.
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Appetite depressants.
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Appetite -- Effect of drugs on.
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Appetite Regulation
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Appetite Depressants
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Appetite -- drug effects
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Appetite
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MEDICAL -- Physiology.
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SCIENCE -- Life Sciences -- Human Anatomy & Physiology.
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Appetite
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Appetite depressants
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Appetite -- Effect of drugs on
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| Form |
Electronic book
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| Author |
Joost, Hans-Georg
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| ISBN |
9783642247163 |
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3642247164 |
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